Protein Info for MPMX20_04374 in Enterobacter sp. TBS_079

Annotation: putative 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 134 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 42 to 68 (27 residues), see Phobius details amino acids 77 to 98 (22 residues), see Phobius details amino acids 104 to 123 (20 residues), see Phobius details

Best Hits

Swiss-Prot: 66% identical to ARNF_KLEP7: Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF (arnF) from Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)

KEGG orthology group: K12963, undecaprenyl phosphate-alpha-L-ara4N flippase subunit ArnF (inferred from 85% identity to enc:ECL_04857)

MetaCyc: 50% identical to undecaprenyl-phosphate-alpha-L-Ara4N flippase - ArnF subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-276

Predicted SEED Role

"Polymyxin resistance protein PmrM" in subsystem Lipid A-Ara4N pathway ( Polymyxin resistance )

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (134 amino acids)

>MPMX20_04374 putative 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF (Enterobacter sp. TBS_079)
MRGTFWALCSVMLVSAAQLLLRYAMQALPPVSELYAFVSALWHLSSGTGALLLGLMGYVA
SMGCWYLALHRMALSKAYALLSLSYILVWAAAILLPGWNEHFSWHGLAGVGMIILGVLVI
FMPRTSRGEQSSRR