Protein Info for MPMX20_04172 in Enterobacter sp. TBS_079

Annotation: putative signaling protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 697 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 39 to 63 (25 residues), see Phobius details amino acids 76 to 97 (22 residues), see Phobius details amino acids 108 to 129 (22 residues), see Phobius details amino acids 141 to 160 (20 residues), see Phobius details amino acids 172 to 192 (21 residues), see Phobius details amino acids 212 to 234 (23 residues), see Phobius details PF03707: MHYT" amino acids 52 to 108 (57 residues), 72.8 bits, see alignment 2.8e-24 amino acids 115 to 169 (55 residues), 62.1 bits, see alignment 6.1e-21 amino acids 182 to 240 (59 residues), 25.9 bits, see alignment 1.2e-09 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 257 to 419 (163 residues), 136.8 bits, see alignment E=3e-44 PF00990: GGDEF" amino acids 261 to 416 (156 residues), 148.5 bits, see alignment E=2.2e-47 PF00563: EAL" amino acids 438 to 672 (235 residues), 242.3 bits, see alignment E=7e-76

Best Hits

Swiss-Prot: 60% identical to Y1727_PSEAE: Uncharacterized signaling protein PA1727 (PA1727) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 94% identity to enc:ECL_04648)

Predicted SEED Role

"FIG00554530: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (697 amino acids)

>MPMX20_04172 putative signaling protein (Enterobacter sp. TBS_079)
MLVSQYNHILVVLSFVVAILAAYTALNMAARVAGSQGVAARVWLAGGGIAMGIGVWAMHF
IGMLAMDLSMSMRYNATLTVLSMVIAVGSSLFALWLVSCEQLRLRRLLPGALVMGCGIVA
MHYTGMAALEVSHGIIWDKTWVAISVVIALAASLAALWLTFRLRHEASQVSLMRFAAAVT
MGIAIAGMHYAGMKAAQFPMSTMTHHEGINGSWLAVLVSVVALAILGITLLVSMLDARLQ
ARTSLLASSLAEANRELAQLALQDTLTRLPNRVLLEDRLDQAISKADREGTHFALMFMDL
DGFKTINDAYGHDVGDRLLVAVTQRLLTPLKGQFTLARIGGDEFVLLAEGEGPDDAASLA
NSLVRAIDSPFNLDPYELVVTLSIGIALYPHDGKTERELMFNADAAMYHTKHMGRNGYHF
FQPSMNTLAQTHLQLMNDLWLAIDRNELRLLYQPKFHAPAGPVLGFEALLRWQHPKQGLL
TPDLFLPLAEKTGLIIPIGNWVLNEACRQLREWHLQGHQNWSMAVNLSTLQFEQPSLVKT
VLDCLTRHNVPPEMLILEVTETTAMSNPDESVRVLTELTDAGVKASIDDFGTGYSSLLYL
KRLPACELKIDRAFVKELSGESEDATIVSAIVALAKTLNLKVVAEGVETEAQQTFLTALG
CNTLQGYLLGKPVSAQTIETLCAQGEMLPGAELKSSS