Protein Info for MPMX20_04166 in Enterobacter sp. TBS_079

Annotation: Sodium/pantothenate symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 483 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 44 to 64 (21 residues), see Phobius details amino acids 74 to 94 (21 residues), see Phobius details amino acids 122 to 144 (23 residues), see Phobius details amino acids 156 to 178 (23 residues), see Phobius details amino acids 190 to 211 (22 residues), see Phobius details amino acids 234 to 257 (24 residues), see Phobius details amino acids 273 to 295 (23 residues), see Phobius details amino acids 318 to 338 (21 residues), see Phobius details amino acids 369 to 386 (18 residues), see Phobius details amino acids 392 to 415 (24 residues), see Phobius details amino acids 423 to 442 (20 residues), see Phobius details amino acids 448 to 466 (19 residues), see Phobius details TIGR02119: sodium/pantothenate symporter" amino acids 4 to 471 (468 residues), 759 bits, see alignment E=2.2e-232 PF00474: SSF" amino acids 36 to 432 (397 residues), 476.4 bits, see alignment E=3.8e-147 TIGR00813: transporter, solute:sodium symporter (SSS) family" amino acids 36 to 432 (397 residues), 378.7 bits, see alignment E=3.9e-117

Best Hits

Swiss-Prot: 92% identical to PANF_ECOLI: Sodium/pantothenate symporter (panF) from Escherichia coli (strain K12)

KEGG orthology group: K14392, sodium/pantothenate symporter (inferred from 95% identity to enc:ECL_04643)

MetaCyc: 92% identical to pantothenate:Na+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-117

Predicted SEED Role

"Pantothenate:Na+ symporter (TC 2.A.21.1.1)" in subsystem Coenzyme A Biosynthesis (TC 2.A.21.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (483 amino acids)

>MPMX20_04166 Sodium/pantothenate symporter (Enterobacter sp. TBS_079)
MQLEVILPLVAYLVVVFGLSVYAMRKRTTGTFLNEYFLGSRSMGGVVLAMTLTATYISAS
SFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILARRYNAVTLNDMLFARYQS
RLLVWLASLSLLVAFIGAMTVQFIGGARLLETAAGIPYETGLIIFGVSIALYTAFGGFRA
SVLNDTLQGMVMLVGTIVLLVGIVHAAGGLSHAVETLEAIDPKLISPQGADDILSPTFMT
SFWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIGTVVVAILMFGMHLAGALGRAVIPD
LTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMSTINAQLLQSSATIIKDLYLNLRPEQV
QNERRLKRMSAVITLVLGALLLLAAWRPPEMIIWLNLLAFGGLEAVFLWPLVLGLYWERA
NAAGALSGMIVGGVLYAVLATFKIQYLGFHPIVPSLLLSLLAFVVGNRFGQPVPQPATIS
TDK