Protein Info for MPMX20_04123 in Enterobacter sp. TBS_079

Annotation: Dihydroxyacetone kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02361: dihydroxyacetone kinase
  • amino acids 3 to 543 (541 residues), 575.7 bits, E=5.8e-177
• PF02733: Dak1
  • amino acids 26 to 323 (298 residues), 334.4 bits, E=5.8e-104
• PF02734: Dak2
  • amino acids 381 to 544 (164 residues), 128.6 bits, E=2.5e-41

Best Hits

KEGG orthology group: K00863, dihydroxyacetone kinase [EC: 2.7.1.29] (inferred from 93% identity to enc:ECL_04599)

Predicted SEED Role

"Dihydroxyacetone kinase, ATP-dependent (EC 2.7.1.29)" in subsystem Dihydroxyacetone kinases (EC 2.7.1.29)

MetaCyc Pathways

• formaldehyde assimilation III (dihydroxyacetone cycle) (11/12 steps found)
• glycerol degradation II (2/2 steps found)
• glycerol degradation to butanol (12/16 steps found)
• superpathway of glycerol degradation to 1,3-propanediol (2/4 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.29

Protein Sequence (548 amino acids)

>MPMX20_04123 Dihydroxyacetone kinase (Enterobacter sp. TBS_079)
MSRFFFNDRKQLVNDAIEGILISAPHANLVKLDIDPAIRVVARSDWDKSRVAVISGGGSG
HEPAHAGFVGKGMLTAAVCGDLFASPSVDAVLNAIVAVTGDRGCLLIVKNYTGDRLNFGL
AAEKAKRYGLKVEMVIVADDIALPDNKQPRGIAGTALVHKIAGYAAEHGKSLTEVRDIAQ
QACDNLWSLGVAMQTCNLPGSDDEEGRIKQGHVELGLGIHGEPGASVVDTQNSKAIIDTL
VEPLKAQAGNGRFAVLINNLGGVSALEMALLTKELAHSALKENIAYLIGPAPLVSALDMK
GFSLTLLKLNDLFEKALHEEVETLGWQKPVAFAPLRVQEHSAIHDRVEYTASDNPRVAEI
VSTVTQTLIQLENRLNALDAKVGDGDTGSTFAQGARDIAQRLEKKQLPLNDVSTLLLLVG
ERLATVMGGSSGVLMSIFFTAAGQTLHDGQPLPEALLSGLAQMKQYGGADLGDRTLIDAL
QPALEALQKGDLQAAAQAANAGAEATANMVKAGAGRSSYVNKENLEGVTDPGAVAVAEVF
KAMTAAKR