Protein Info for MPMX20_03867 in Enterobacter sp. TBS_079

Annotation: Unsaturated chondroitin disaccharide hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF07470: Glyco_hydro_88
  • amino acids 58 to 255 (198 residues), 34.7 bits, E=5.1e-13

Best Hits

Swiss-Prot: 47% identical to UCDH_STRR6: Unsaturated chondroitin disaccharide hydrolase (ugl) from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)

KEGG orthology group: None (inferred from 91% identity to ent:Ent638_3433)

MetaCyc: 46% identical to unsaturated beta-glucuronyl hydrolase (Streptococcus agalactiae)
RXN-12177 [EC: 3.2.1.180]; RXN-16485 [EC: 3.2.1.180, 3.2.1.179]; 3.2.1.179 [EC: 3.2.1.180, 3.2.1.179]

Predicted SEED Role

"Unsaturated glucuronyl hydrolase (EC 3.2.1.-)" (EC 3.2.1.-)

MetaCyc Pathways

• hyaluronan degradation (1/2 steps found)
• dermatan sulfate degradation I (bacterial) (1/4 steps found)
• chondroitin sulfate degradation I (bacterial) (2/8 steps found)

KEGG Metabolic Maps

• Ascorbate and aldarate metabolism
• Glycosaminoglycan degradation
• Nucleotide sugars metabolism
• Ubiquinone and menaquinone biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.- or 3.2.1.179 or 3.2.1.180

Protein Sequence (395 amino acids)

>MPMX20_03867 Unsaturated chondroitin disaccharide hydrolase (Enterobacter sp. TBS_079)
MLSRIAEERLPAIPVPVDSRVFRDELSSARDHVLALISRHLTAFGEQFPAETCQQGFYPL
TDNVEWTTSFWTGQLWLAWEMSGEAKFRAMAEKHVRSFGLRIAGRHDTNTHDLGFLYTLS
CVAAWRLTGNREARGFSLLAAEALLERFHEKAKIIQAWGDLADPEQAGRMIIDCNMNLPL
LYWASEQTGDPRFADAAKAHVMQAARYLIREDASTFHTYYMDVHTGAPRYGNTQQGYADD
SCWSRGQAWGIYGFLLSYIYTGDATMIALSKRLANYFLNRLPEDYVCHWDLALVGTDALR
DASSAAIAICGLLELVKHLPVTDPDRERYSEWAKGMMSSLTKHYLMGKDEKGTGLLKHSV
YHLASNKGVDECASWGDYFYVEALVRFTQSWKLYW