Protein Info for MPMX20_03453 in Enterobacter sp. TBS_079

Annotation: Peptidyl-lysine N-acetyltransferase Pat

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 887 PF13380: CoA_binding_2" amino acids 13 to 130 (118 residues), 81.8 bits, see alignment E=1.3e-26 PF13607: Succ_CoA_lig" amino acids 147 to 280 (134 residues), 154.2 bits, see alignment E=4.8e-49 PF13549: ATP-grasp_5" amino acids 472 to 693 (222 residues), 245.5 bits, see alignment E=1e-76 PF13302: Acetyltransf_3" amino acids 725 to 863 (139 residues), 33.9 bits, see alignment E=1.2e-11 PF00583: Acetyltransf_1" amino acids 759 to 863 (105 residues), 41.4 bits, see alignment E=4.2e-14

Best Hits

Swiss-Prot: 87% identical to LYSAC_SALTY: Peptidyl-lysine N-acetyltransferase Pat (pat) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K09181, hypothetical protein (inferred from 97% identity to enc:ECL_03920)

MetaCyc: 86% identical to peptidyl-lysine N-acetyltransferase (Escherichia coli K-12 substr. MG1655)
2.3.1.-

Predicted SEED Role

"Protein acetyltransferase" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (887 amino acids)

>MPMX20_03453 Peptidyl-lysine N-acetyltransferase Pat (Enterobacter sp. TBS_079)
MSQRGLEALLRPKSIAVIGASMKPDRAGYLMMRNLLAGGFNGPVMPVTPAYKAVQGVLAW
PDVQSLPFIPDLAILCTNAKRNPALLESLGRKGCKTCIILSSPPEQQPELLACASRYQMR
ILGPNSLGLLAPWQGLNASFSPVPIRQGKLAFISQSAAVSNTILDWAQQREMGFSYFIAL
GDSLDIDVDELLDFLARDSKTSAILLYLEHLSDARRFVSASRSASRNKPILVIKSGRSPA
AQRLLQSHSGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGEKLMIVSNGAAP
AALALDELWLRNGKLATLGEETLQRLKEALPASVSPGNPLDLRDDASSDHYIRAISLLLD
SQDFDALMIIHSPSAVAPGSESARALIDAVRNHPRGKYVTLLTNWCGEFSSQEARRLFSE
AGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPALPGNLTANTADVHRLLQQAIEEGATS
LDTHEVQPILGSYGMQTLPTWIAGDSAEAVHIAEQIGYPVALKLRSPDIPHKSDVQGVML
YLRTATEVQQAADAIFDRVKMAWPQARIHGLLVQSMANRAGAQELRVVVEYDPVFGPLIM
LGEGGVEWRPEEQAVVALPPLNMNLARYLIIQAIKSKKIRGRSALRPLDIAGLSQFLVQV
SNLIVDCAEIQRLDIHPLLASGSEFTALDVTLDIAPFEGDRESRLAIRPYPLQLEEWVEM
KNGERALFRPILPEDEPQLRTFISQVTKEDLYYRYFSEINEFTHDDLANMTQIDYDREMA
FVAVRRSDKGDEILGVTRAISDPDNVDAEFAVLVRSDLKGLGLGRRLLEKLISYTRDHGL
LRLNGITMPNNRGMVTLARKLGFDVDIQLDEGIVALSLSLISADKAE