Protein Info for MPMX20_03299 in Enterobacter sp. TBS_079

Annotation: Xanthosine permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 42 to 62 (21 residues), see Phobius details amino acids 71 to 88 (18 residues), see Phobius details amino acids 94 to 115 (22 residues), see Phobius details amino acids 135 to 154 (20 residues), see Phobius details amino acids 160 to 182 (23 residues), see Phobius details amino acids 211 to 232 (22 residues), see Phobius details amino acids 254 to 275 (22 residues), see Phobius details amino acids 282 to 301 (20 residues), see Phobius details amino acids 307 to 327 (21 residues), see Phobius details amino acids 347 to 369 (23 residues), see Phobius details amino acids 382 to 402 (21 residues), see Phobius details TIGR00889: nucleoside transporter" amino acids 1 to 418 (418 residues), 658.7 bits, see alignment E=2.1e-202 PF03825: Nuc_H_symport" amino acids 1 to 405 (405 residues), 565 bits, see alignment E=1.9e-173 PF12832: MFS_1_like" amino acids 5 to 374 (370 residues), 94.3 bits, see alignment E=1.7e-30 PF01306: LacY_symp" amino acids 9 to 400 (392 residues), 38.9 bits, see alignment E=1e-13 PF07690: MFS_1" amino acids 254 to 411 (158 residues), 44.3 bits, see alignment E=2.4e-15

Best Hits

Swiss-Prot: 76% identical to XAPB_ECOLI: Xanthosine permease (xapB) from Escherichia coli (strain K12)

KEGG orthology group: K11537, MFS transporter, NHS family, xanthosine permease (inferred from 87% identity to ent:Ent638_2933)

MetaCyc: 76% identical to xanthosine:H+ symporter XapB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-31

Predicted SEED Role

"Xanthosine permease" in subsystem Xanthosine utilization (xap region)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (418 amino acids)

>MPMX20_03299 Xanthosine permease (Enterobacter sp. TBS_079)
MNITTRLKMMSFMQYFIWGSWLVTLGAYMINTLGFSGSDVGMVYSSKGLAAIVMPSLVGI
IADKWLRADRAYVICHLVCAVALCYAAQVNEPGLMFWVMLVNAMAFMPTIALSNTISYSC
LEQAGLDTVTHFPTVRVYGTVGFIVAMWAISLMGAELTNIQLYIAAAASLVLALYSLTLP
AIPVAKNKTSSSLASKLGLNAFVLFKQPRMAVFFLFAMLLGAVLQITNTFGSPFLHDFAR
NPAYAESFIVKYPSILLSVSQMSEVLFILTIPFFLRRFGIKTVMLMSMVAWMLRFGLFAY
GDPSATGVGLLMLSMLVYGCAFDFFNISGSVFVEQEVSADIRASAQGLFMTTVNGIGAYF
GSVLSGAAVDYFSVDGVKDWQTIWLVFAAYALVLAVVFYFSFNYRQTSKNSELRTVAH