Protein Info for MPMX20_03177 in Enterobacter sp. TBS_079

Annotation: Transcriptional regulatory protein RcsB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 216 PF00072: Response_reg" amino acids 6 to 120 (115 residues), 75.9 bits, see alignment E=2.8e-25 PF00196: GerE" amino acids 151 to 201 (51 residues), 45.5 bits, see alignment E=4.7e-16

Best Hits

Swiss-Prot: 98% identical to RCSB_SHIFL: Transcriptional regulatory protein RcsB (rcsB) from Shigella flexneri

KEGG orthology group: K07687, two-component system, NarL family, captular synthesis response regulator RcsB (inferred from 100% identity to enc:ECL_03521)

Predicted SEED Role

"DNA-binding capsular synthesis response regulator RcsB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (216 amino acids)

>MPMX20_03177 Transcriptional regulatory protein RcsB (Enterobacter sp. TBS_079)
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP
GDKYGDGITLIKYIKRHFPDISIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKAL
AALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIK
TISSQKKSAMMKLGVDNDIALLNYLSSVTLSASDKD