Protein Info for MPMX20_02983 in Enterobacter sp. TBS_079

Annotation: HTH-type transcriptional regulator ArgP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 PF00126: HTH_1" amino acids 3 to 62 (60 residues), 73.6 bits, see alignment E=1e-24 PF03466: LysR_substrate" amino acids 87 to 287 (201 residues), 115.6 bits, see alignment E=2.1e-37

Best Hits

Swiss-Prot: 92% identical to NAC_KLEAE: Nitrogen assimilation regulatory protein nac (nac) from Klebsiella aerogenes

KEGG orthology group: None (inferred from 100% identity to enc:ECL_03324)

Predicted SEED Role

"Nitrogen assimilation regulatory protein Nac" in subsystem DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (305 amino acids)

>MPMX20_02983 HTH-type transcriptional regulator ArgP (Enterobacter sp. TBS_079)
MNLRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGEMDQQLLIRTKRGVTPTEA
GKILYTHARTILRQCEQAQLAVNNVGQTLSGHVSIGLAPGTAASSITMPLLQAVRAELPE
VLVYLHENSGSVLNDKLLSGQLDMAVLYDRSPVAGITSQPLLKEDLYLVGTRDCPGQSVD
LTAVAEMNLFLPRDYSAVRVRVDEAFSLRRLTAKIIGEIDSISTLTAAIASGMGVTVLPE
SAARSLCSAANGWMARITTPSMSLPLSLNMSARGSLSPQAQAVKEILMSLVSKPSLENRE
LQLVS