Protein Info for MPMX20_02798 in Enterobacter sp. TBS_079

Annotation: Chemotaxis protein CheA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 677 PF01627: Hpt" amino acids 8 to 97 (90 residues), 70.1 bits, see alignment E=4e-23 PF09078: CheY-binding" amino acids 165 to 227 (63 residues), 64.2 bits, see alignment E=2.3e-21 PF02895: H-kinase_dim" amino acids 285 to 347 (63 residues), 73.2 bits, see alignment E=4.7e-24 PF02518: HATPase_c" amino acids 395 to 531 (137 residues), 65.9 bits, see alignment E=1.1e-21 PF01584: CheW" amino acids 537 to 663 (127 residues), 103.8 bits, see alignment E=1.5e-33

Best Hits

KEGG orthology group: K03407, two-component system, chemotaxis family, sensor kinase CheA [EC: 2.7.13.3] (inferred from 96% identity to enc:ECL_01404)

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (677 amino acids)

>MPMX20_02798 Chemotaxis protein CheA (Enterobacter sp. TBS_079)
MSMDISDFYQTFFDEADELLADMEQHLLDLVPEAPDSEQLNAIFRAAHSIKGGAGTFGFT
ILQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQLDAYKSSAEPDAASFEYIC
NALRQLALEAKGDAAAAVVPAAKLSVVDAVTAQEAAPAAAASKVRVVLSRLKENEVDLLE
EELSNLAKLSNVVKGKDSLSATLEEGISQDDIVAVLCFVIEADQIAFETETAAVDVPAAV
EEVAVVPQAAAPAVAPAAPVLKAVPKDAAAPGRGDKPAARSSESTSIRVAVEKVDQLINL
VGELVITQSMLAQRSNELDPVTHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFSRFP
RLVRDLASKLNKQIELTLMGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPENRIAAGK
SPVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAISQGMAVNENMTDEEVGMLIFAP
GFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVEIKSKQGSGTTIRILLPLTLAILDGMSV
KVADEVFILPLNAVMESLQPREEDLHPLAGGERVLEVRGEYLPLVELWKVFEVDGAKTEA
TQGIVVILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDV
SALQGLNREQRVAYTAA