Protein Info for MPMX20_02764 in Enterobacter sp. TBS_079

Annotation: Zinc import ATP-binding protein ZnuC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 251 PF00005: ABC_tran" amino acids 20 to 149 (130 residues), 103 bits, see alignment E=2.2e-33

Best Hits

Swiss-Prot: 92% identical to ZNUC_SALPA: Zinc import ATP-binding protein ZnuC (znuC) from Salmonella paratyphi A (strain ATCC 9150 / SARB42)

KEGG orthology group: K09817, zinc transport system ATP-binding protein [EC: 3.6.3.-] (inferred from 97% identity to enc:ECL_01440)

MetaCyc: 92% identical to Zn2+ ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-63-RXN [EC: 7.2.2.20]

Predicted SEED Role

"Zinc ABC transporter, ATP-binding protein ZnuC" in subsystem Transport of Zinc

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.- or 7.2.2.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (251 amino acids)

>MPMX20_02764 Zinc import ATP-binding protein ZnuC (Enterobacter sp. TBS_079)
MTTLVSLDNISVSFGQRRVLSDVSLDLKPGKILTLLGPNGAGKSTLVRVVLGLVTPDEGV
IRREEKLRIGYVPQKLHLDATLPLTVSRFLRLRPGTHKADILPALKRVQAGHLIDAPLQK
LSGGETQRVLLARALLSSPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELNCAVLMVSHD
LHLVMAKTDEVLCLNHHICCSGTPEVVSMHPEFISMFGPRGAEQLGIYRHHHNHRHDLQG
RIVLRRGNGHS