Protein Info for MPMX20_02441 in Enterobacter sp. TBS_079

Annotation: ATP-dependent RNA helicase DbpA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 PF00270: DEAD" amino acids 27 to 192 (166 residues), 160.2 bits, see alignment E=7.8e-51 PF04851: ResIII" amino acids 30 to 187 (158 residues), 29.3 bits, see alignment E=1.6e-10 PF00271: Helicase_C" amino acids 228 to 336 (109 residues), 104 bits, see alignment E=1.1e-33 PF03880: DbpA" amino acids 384 to 454 (71 residues), 74.6 bits, see alignment E=1.1e-24

Best Hits

Swiss-Prot: 91% identical to DBPA_ECOLI: ATP-dependent RNA helicase DbpA (dbpA) from Escherichia coli (strain K12)

KEGG orthology group: K05591, ATP-independent RNA helicase DbpA [EC: 3.6.4.13] (inferred from 96% identity to enc:ECL_01829)

MetaCyc: 91% identical to ATP-dependent RNA helicase DbpA (Escherichia coli K-12 substr. MG1655)
5.6.2.e [EC: 5.6.2.e]

Predicted SEED Role

"ATP-dependent 23S rRNA helicase DbpA"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13 or 5.6.2.e

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (457 amino acids)

>MPMX20_02441 ATP-dependent RNA helicase DbpA (Enterobacter sp. TBS_079)
MTAFSTLNVLPAAQLDNLNELGYLTMTPVQAATLPAILEGRDVRVQAKTGSGKTAAFGLG
LLQHIDAALFQTQSLVLCPTRELADQVAGELRRLARFLPNTKILTLCGGQPFGAQRDSLQ
HPPHIIVATPGRLLDHLQKGTVSLDALHTLVMDEADRMLDMGFSDAIDEVIRFAPADRQT
LLFSATWPEAIAAISGRVQKNPLTIEIDSVDALPAIEQQFYETSQHGKIALLQKVLSQHQ
PASCVVFCNTKKDCQAVCDALNAAGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDV
AARGLDIKSLELVVNYELAWDPEVHVHRIGRTARAGNSGLAISFCAPEEAQRANILSEML
QIKLNWVNAPGNVSLVPLEAEMATLCIDGGKKAKMRPGDVLGALTGDVGLDGADIGKITV
HPAHVYVAVRQSVAHKAWKQLQNGKIKGKTCRVRLLK