Protein Info for MPMX20_02412 in Enterobacter sp. TBS_079

Annotation: L-amino acid N-acyltransferase MnaT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13302: Acetyltransf_3
  • amino acids 2 to 137 (136 residues), 44.7 bits, E=6.6e-15
• PF13420: Acetyltransf_4
  • amino acids 4 to 155 (152 residues), 51.3 bits, E=4.2e-17
• PF00583: Acetyltransf_1
  • amino acids 22 to 136 (115 residues), 74.1 bits, E=3.4e-24
• PF13673: Acetyltransf_10
  • amino acids 50 to 142 (93 residues), 37.9 bits, E=4.8e-13
• PF13508: Acetyltransf_7
  • amino acids 53 to 137 (85 residues), 50.5 bits, E=6.8e-17
• PF08445: FR47
  • amino acids 84 to 137 (54 residues), 37.3 bits, E=6.6e-13

Best Hits

Swiss-Prot: 84% identical to MNAT_ECOLI: L-amino acid N-acyltransferase MnaT (mnaT) from Escherichia coli (strain K12)

KEGG orthology group: K03823, phosphinothricin acetyltransferase [EC: 2.3.1.183] (inferred from 95% identity to enc:ECL_01863)

MetaCyc: 84% identical to L-amino acid N-acyltransferase (Escherichia coli K-12 substr. MG1655)
Amino-acid N-acetyltransferase. [EC: 2.3.1.1]

Predicted SEED Role

"Putative acetyltransferase"

MetaCyc Pathways

• superpathway of arginine and polyamine biosynthesis (16/17 steps found)
• L-arginine biosynthesis I (via L-ornithine) (9/9 steps found)
• L-arginine biosynthesis II (acetyl cycle) (9/10 steps found)
• L-arginine biosynthesis III (via N-acetyl-L-citrulline) (8/9 steps found)
• L-ornithine biosynthesis I (5/5 steps found)
• phosalacine biosynthesis (2/25 steps found)
• phosphinothricin tripeptide biosynthesis (2/25 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Urea cycle and metabolism of amino groups

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.1, 2.3.1.183

Use Curated BLAST to search for 2.3.1.1 or 2.3.1.183

Protein Sequence (172 amino acids)

>MPMX20_02412 L-amino acid N-acyltransferase MnaT (Enterobacter sp. TBS_079)
MIVRHACKEDCAAIGEIYNHAVLHTAAIWNDKTVDTDNRIAWFEARALAGYPVLVSEENG
VITGYASFGDWRAFDGFRHTVEHSVYVHPDHQGKGIGRTLMNALIIEARTLGKHVMVAGI
EAQNQASIHLHETLGFVTTGQMPQVGTKFGRWLDLTFMQLQLDERSDPDAIS