Protein Info for MPMX20_02383 in Enterobacter sp. TBS_079

Annotation: Methyl viologen resistance protein SmvA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 495 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 21 to 25 (5 residues), see Phobius details amino acids 43 to 64 (22 residues), see Phobius details amino acids 73 to 92 (20 residues), see Phobius details amino acids 97 to 119 (23 residues), see Phobius details amino acids 131 to 152 (22 residues), see Phobius details amino acids 158 to 181 (24 residues), see Phobius details amino acids 193 to 212 (20 residues), see Phobius details amino acids 223 to 241 (19 residues), see Phobius details amino acids 260 to 280 (21 residues), see Phobius details amino acids 298 to 319 (22 residues), see Phobius details amino acids 326 to 345 (20 residues), see Phobius details amino acids 355 to 379 (25 residues), see Phobius details amino acids 398 to 420 (23 residues), see Phobius details amino acids 469 to 490 (22 residues), see Phobius details PF07690: MFS_1" amino acids 12 to 403 (392 residues), 131.6 bits, see alignment E=1.7e-42

Best Hits

Swiss-Prot: 79% identical to SMVA_SALT1: Methyl viologen resistance protein SmvA (smvA) from Salmonella typhimurium (strain 14028s / SGSC 2262)

KEGG orthology group: K08167, MFS transporter, DHA2 family, methyl viologen resistance protein SmvA (inferred from 92% identity to enc:ECL_01896)

Predicted SEED Role

"Methyl viologen resistance protein smvA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (495 amino acids)

>MPMX20_02383 Methyl viologen resistance protein SmvA (Enterobacter sp. TBS_079)
MFRQWLALVIIVLVYIPVAIDATVLHVAAPTLSMTLGASGNELLWIIDIYSLVMAGMVLP
MGALGDRIGFKRLLIIGSTLFGLSSLAAAFAPSAGWLIAARASLAIGAAMIIPATLAGIR
TLFVNARDRNIALGVWAAVGSGGAAFGPLIGGMLLEHFYWGSVFLINVPIVVIVVSLAAR
LVPRQQGRPEQPLNIAHAIMLIVAILLLVYSAKTALKGVLSRWLVAMTLLTGAVMLMIFV
RIQLRARVPMIDMRLFCHRIILSGVVMAMTAMIALVGFELLMAQELQFVHGFTPFEAGMF
MLPLMVASGFSGPIAGVLVGRLGLRLVAAGGMGLSAVSFIGLSMLDFSTQHWQAWSLMVL
LGFSAASALLASTSAIMAAAPKEKAAAAGAIETMSYELGAGLGIAIFGLLLTRSFSASIV
LPQGLSATLADKASSSIGEAVNVAQSLTPGLAESLIAAAKTAFITSHSVALGSAGAMLLV
LAVGIWFSLANVPKQ