Protein Info for MPMX20_02284 in Enterobacter sp. TBS_079

Annotation: Trans-aconitate 2-methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 PF13489: Methyltransf_23" amino acids 12 to 176 (165 residues), 51.5 bits, see alignment E=3.5e-17 PF01728: FtsJ" amino acids 22 to 94 (73 residues), 27 bits, see alignment E=1.4e-09 PF05175: MTS" amino acids 23 to 78 (56 residues), 23.4 bits, see alignment E=1.5e-08 PF13847: Methyltransf_31" amino acids 33 to 134 (102 residues), 41.9 bits, see alignment E=3.1e-14 PF13649: Methyltransf_25" amino acids 35 to 122 (88 residues), 56.3 bits, see alignment E=1.6e-18 PF08242: Methyltransf_12" amino acids 36 to 126 (91 residues), 40.6 bits, see alignment E=1.2e-13 PF08241: Methyltransf_11" amino acids 36 to 128 (93 residues), 46.1 bits, see alignment E=2.2e-15

Best Hits

Swiss-Prot: 79% identical to TAM_ENT38: Trans-aconitate 2-methyltransferase (tam) from Enterobacter sp. (strain 638)

KEGG orthology group: K00598, trans-aconitate 2-methyltransferase [EC: 2.1.1.144] (inferred from 92% identity to enc:ECL_01974)

MetaCyc: 78% identical to trans-aconitate 2-methyltransferase (Escherichia coli K-12 substr. MG1655)
Trans-aconitate 2-methyltransferase. [EC: 2.1.1.144]

Predicted SEED Role

"Trans-aconitate 2-methyltransferase (EC 2.1.1.144)" (EC 2.1.1.144)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.144

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (252 amino acids)

>MPMX20_02284 Trans-aconitate 2-methyltransferase (Enterobacter sp. TBS_079)
MADWNPSLYLRYGAERTRPAAELLARIPLDDVSSIVDLGCGPGNSTALLKHRWPSAHVTG
VDNSPAMLDEARSALPDCHFVEADIRQFKPGQPLSLIYANASLQWVPDHYDLLPHLVSLL
TLNGVLAIQMPDNWLEPTHVAMREVAWEQGYPDRGREALPGVHAYYDILTDAGCDVDIWR
TTYFHKMSSHQAIIDWVSATGLRPWLQELNESEQKRFLKRYHEMLEEQYPLQENGQILLA
FPRLFIIAQRQP