Protein Info for MPMX20_02211 in Enterobacter sp. TBS_079

Annotation: Quinate/shikimate dehydrogenase (quinone)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 793 transmembrane" amino acids 13 to 36 (24 residues), see Phobius details amino acids 43 to 61 (19 residues), see Phobius details amino acids 67 to 86 (20 residues), see Phobius details amino acids 93 to 112 (20 residues), see Phobius details amino acids 124 to 145 (22 residues), see Phobius details TIGR03074: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family" amino acids 19 to 790 (772 residues), 1079.8 bits, see alignment E=0 PF01011: PQQ" amino acids 227 to 258 (32 residues), 25.1 bits, see alignment (E = 1.1e-09) amino acids 444 to 470 (27 residues), 26.7 bits, see alignment (E = 3.4e-10) amino acids 722 to 754 (33 residues), 22 bits, see alignment (E = 1.1e-08) PF13360: PQQ_2" amino acids 365 to 527 (163 residues), 23.4 bits, see alignment E=4.3e-09 amino acids 667 to 752 (86 residues), 24.9 bits, see alignment E=1.5e-09

Best Hits

KEGG orthology group: K05358, quinate dehydrogenase (quinone) [EC: 1.1.5.8] (inferred from 94% identity to enc:ECL_02057)

Predicted SEED Role

"Quinate/shikimate dehydrogenase [Pyrroloquinoline-quinone] (EC 1.1.99.25)" in subsystem Chorismate Synthesis or Quinate degradation (EC 1.1.99.25)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.5.8 or 1.1.99.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (793 amino acids)

>MPMX20_02211 Quinate/shikimate dehydrogenase (quinone) (Enterobacter sp. TBS_079)
MAFGSAPRGIPRILQWLLVGLMTLIGLAVGGLGLKLVTVGGSGYFLIMGVAMVIAAVLIF
INRASGIVLYGIAFIASLFWAVSDAGWDFWPLFSRLFTFAVLAFLCAIVWPFMRAANHNA
PNKAPAFGVAAVLAVVMLVSLGWMFKPQTLVVANEPVPVKPVAPGQEQKNWAHWGNTTHG
DRFAALDQINKQNVKDLKVAWVAHTGDIPQSNGSGAEDQNTPLQIGDTLYVCTPYSKVLA
LDVDSGKEKWRYDAKASAPNWQRCRGLGYFEDHSIVTTSQADAQPAACPRRLFLPTTDAR
LIAINADNGKVCEDFGDRGTVDLSIGMGEIKPGYYQQTSTPLVAGNVVVVGGRIADNFST
GEPPGVVRAYDVHTGKLAWAWDPGNPQLTGLPPEGQTYTRGTPNVWSAMSYDAKLNLIYL
PTGNATPDFWAGERTALDDKYSSSIVAVDAATGQVRWHFQTTHHDLWDFDLPSQPLLYDL
PDGKGGTTPVLVQTSKQGMIFMLNRETGKPVAKVEERPVPAGNVEGERYSPTQPYSVGMP
MIGNQTLTESDMWGATPVDLLLCRIQFKEMRHQGVFTPPGLDRSLQFPGSLGGMNWGSVS
IDPNNSLMFVNDMRLGLANYMVPRANVAKNASGIEMGIVPMDGTPFGAMRERFLSPLGIP
CQKPPFGTMSAVDLKSGKLVWQVPVGTVEDTGPLGIRMHMPIPIGMPTLGASLATQSGLL
FFAGTQDFYLRAFDTATGKEIWKDRLPVGSQSGPMTYVSPKTGKQYIIINAGGARQSPDR
GDYVIAYALPDKQ