Protein Info for MPMX20_02202 in Enterobacter sp. TBS_079

Annotation: Type I secretion system membrane fusion protein PrsE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details PF00529: CusB_dom_1" amino acids 28 to 334 (307 residues), 33.1 bits, see alignment E=8.8e-12 PF13533: Biotin_lipoyl_2" amino acids 60 to 93 (34 residues), 26.8 bits, see alignment 7.2e-10 TIGR01843: type I secretion membrane fusion protein, HlyD family" amino acids 189 to 391 (203 residues), 217.4 bits, see alignment E=1.8e-68 PF16576: HlyD_D23" amino acids 194 to 322 (129 residues), 31.7 bits, see alignment E=1.9e-11 PF13437: HlyD_3" amino acids 241 to 349 (109 residues), 59.1 bits, see alignment E=1.3e-19

Best Hits

KEGG orthology group: K02022, (no description) (inferred from 95% identity to enc:ECL_02073)

Predicted SEED Role

"Type I secretion system, membrane fusion protein LapC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (391 amino acids)

>MPMX20_02202 Type I secretion system membrane fusion protein PrsE (Enterobacter sp. TBS_079)
MTDFSRVNSRLKEPRLPRSTWVAWSLFALLAVFITWASLFSLDEVTTGSGKVIPSSHEQV
IQSLEGGIIHSLLVREGDIVERGQQLAQLDRTKTESSVLESESRLNAALATASRLKAEVN
DTALAFPAELDDDVELVKQETALYQSRRESLEKGLAGLRQGAELVQRELSLTRPLVTQGA
ASKVEVLRLERQKNELENKITEMKNQYYVRAREELAKANAEIEAQRSVMKGREDSLTRLT
FNAPVRGIVKDIDVTTVGGVIPPNGKLMSLVPLDDQMVIEAKISPRDVAFIHPGQKALVK
VTAYDYSIYGGLEGEVTMISPDTLQDEVKRDVYYYRVYIRTDSNHLTNKQGKTFPVFPGM
IATVDIKTGNKTILDYLLKPLNKAKEALRER