Protein Info for MPMX20_02160 in Enterobacter sp. TBS_079

Annotation: Nickel and cobalt resistance protein CnrA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1019 signal peptide" amino acids 1 to 41 (41 residues), see Phobius details transmembrane" amino acids 339 to 357 (19 residues), see Phobius details amino acids 363 to 383 (21 residues), see Phobius details amino acids 393 to 415 (23 residues), see Phobius details amino acids 431 to 454 (24 residues), see Phobius details amino acids 467 to 489 (23 residues), see Phobius details amino acids 528 to 548 (21 residues), see Phobius details amino acids 861 to 879 (19 residues), see Phobius details amino acids 886 to 908 (23 residues), see Phobius details amino acids 914 to 935 (22 residues), see Phobius details amino acids 963 to 983 (21 residues), see Phobius details amino acids 989 to 1013 (25 residues), see Phobius details PF00873: ACR_tran" amino acids 9 to 1011 (1003 residues), 510.6 bits, see alignment E=4.1e-157

Best Hits

KEGG orthology group: None (inferred from 86% identity to ent:Ent638_1874)

Predicted SEED Role

"Cation efflux system protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1019 amino acids)

>MPMX20_02160 Nickel and cobalt resistance protein CnrA (Enterobacter sp. TBS_079)
MSGGRFNLSALAVRERSVTLFLIILVTLAGIFSFFGLGRAEDPPFTVKQMTVITVWPGAT
AQEIQDQVAEPLEKRLQELKWYDRTETYTRPGMAFITLSLQDKTPPSQVQEEFYQARKKL
GDETKNLPAGVMGPMINDEFSDVTFALFALKAKGEPQRLLVRDAEALRQQLLHVPGVKKV
NIIGEQAERIYISFSHDRLATLGLSPQDIFTTLNSQNALTAAGSIETRGAQIFIRLDGAF
DKLQKIRDTPLIAQGKTLRLSDVATVERGYEDPPTLQIRNQQEPTLLLGIVMREGWNGLA
LGKALDAETANINANMPLGMTLTKVTDQSVNIRSSVDEFMIKFFVALLVVMVVCFVSMGW
RVGIVVAAAVPLTLAVVFVVMEASGINFDRVTLGSLILALGLLVDDAIIAIEMMVVKMEE
GYDRIKASAYAWSHTAAPMLAGTLVTAIGFMPNGFAQSTAGEYTSNMFWVVGLALIASWF
VAVVFTPYLGVKILPDIAKVEGGHAAIYDTPRYNRFRHTLSRVIARKWIVAASVVAIFTL
AVLGMGLVKKQFFPTSDRPEVLVEVQMPYGTSIEQTSAATAKIEAWLRKQPEASIVTAYI
GQGSPRFYLAMAPELPDPSFAKVVVMTDSEKSREALKFRLREAVARGLAPEARVRVTQLV
FGPYSPFPVAWRVMGPDVNKLRDIADNVKGVLQASPMMRTVNTDWGSRVPTLHFTLDQNR
LQATGLTSNAVAQQLQFLLSGVPITSVREDIRSVQVTGRAAGDIRLDPAKIEGFTLVGNA
GQRVPLSQIGEIEIRMEDPLLRRRDRTPTITVRGDIAENLQPPDVSTAIMKQLQPIVDSL
PPGYRIEMAGSIEESGKATQAMAPLFPIMIALTLLIIILQVRSLSAMVMVFLTAPLGLIG
VVPTLLLFNQPFGINALVGLIALSGILMRNTLILIGQIDHNQKDGLDPFHAVVEATVQRA
RPVLLTAMAAVLAFIPLTHSVFWGTLAYTLIGGTLGGTIITLVFLPAMYAIWFRIKPAA