Protein Info for MPMX20_01988 in Enterobacter sp. TBS_079

Annotation: Phosphoethanolamine transferase EptA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 541 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details transmembrane" amino acids 45 to 68 (24 residues), see Phobius details amino acids 75 to 95 (21 residues), see Phobius details amino acids 121 to 139 (19 residues), see Phobius details amino acids 148 to 172 (25 residues), see Phobius details PF08019: EptA_B_N" amino acids 56 to 203 (148 residues), 166.2 bits, see alignment E=5.1e-53 PF00884: Sulfatase" amino acids 235 to 524 (290 residues), 230.5 bits, see alignment E=3e-72

Best Hits

KEGG orthology group: K03760, phosphoethanolamine transferase (inferred from 93% identity to enc:ECL_02330)

Predicted SEED Role

"Phosphoethanolamine transferase EptA specific for the 1 phosphate group of core-lipid A" in subsystem Lipid A modifications

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (541 amino acids)

>MPMX20_01988 Phosphoethanolamine transferase EptA (Enterobacter sp. TBS_079)
MWLIKKLQCNDIKFTLGCALFFTVLNALFIQRSWAIIAPAHIHDVLFAASVPLVLFCGWV
IVFSLLNIPFIRKPLLIVLTVGCAAATYFMYTYGAVIDQNMIVNVFETNSQEATALVTPQ
MILWIVVAGLVPSVVLAMIRIRTGKWWYALLTRFAAMLGALLVIILIAALFYKDYASLFR
NNKSIVKMVTPANYVSAMVKYSKMRWFAGDQTLVRIGEDAHKGPLIAGQQKKTVLVLVIG
EASRAANYSLNGYGRETNPELKKQDVINFPQASSCGTETAVSVPCMFSGMTRSKYDADLA
HHQEGLLDVLAHAGINMLWRDNDGGCKGACDRVPHTDMTQWKLDQFCKDNSCIDDVNFTR
LDNVLDGLKQDSVLVIHLMGSHGPAYYRRYPDNFRKFTPTCDTNEIQDCDHQALMNTYDN
TILYTDSMVSKTIDALKARQASMNTALIYLSDHGESLGESGIYLHGTPYLLAPEQQTHIP
FMFWLSPDYAKNFGVNAQCLRDHAAKNAVSQDNLFSTVLGMMDIKSKVYQQQLDILNACR
H