Protein Info for MPMX20_01918 in Enterobacter sp. TBS_079

Annotation: Hemin receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 661 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details TIGR01785: TonB-dependent heme/hemoglobin receptor family protein" amino acids 31 to 661 (631 residues), 574.4 bits, see alignment E=3.5e-176 TIGR01786: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein" amino acids 31 to 661 (631 residues), 448.1 bits, see alignment E=5.8e-138 PF07715: Plug" amino acids 45 to 148 (104 residues), 95.5 bits, see alignment E=2.8e-31 PF00593: TonB_dep_Rec" amino acids 237 to 629 (393 residues), 155.3 bits, see alignment E=4.9e-49

Best Hits

Swiss-Prot: 69% identical to HMUR_YERPE: Hemin receptor (hmuR) from Yersinia pestis

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 91% identity to enc:ECL_02396)

Predicted SEED Role

"TonB-dependent hemin , ferrichrome receptor" in subsystem Hemin transport system or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (661 amino acids)

>MPMX20_01918 Hemin receptor (Enterobacter sp. TBS_079)
MPHLHSAFLRPSCLALSIVSALPGVAFAATDDMTVIATGNARSAFEAPMMVSVIDTAAPE
NQTASSAADLLRYVPGLMLDGTGRTNGQDVNLRGYDRRGVLVLVDGVRQGTDTGHLNSTF
LDPALIKRIEVVRGPSALLYGSGALGGVIAYDTADANDLLEPGKNSGYRVFGTGATGDHS
LGMGASAYGRTETLDGLVAWSSRDRGDLRQSDGGTAPNDESINNMLAKGRWAIDPAQTLS
GSLRYYNNAAQEPKNPQTPAADASSNPMTDRSTIQRDAQLGYHLAPQGNDWLNADAKLYW
SEARINAQNLDGTGEFRKQTTKGGKVENRTRLFSDTFASHLLTYGGEYYRQEQHPGGTTT
GFPEAKIDFSSGWLQDEITLRDLPVTLLGGTRYDNYRGSNEGYDDVNADRWSSRAGLTIS
PTDWLMLFGSYAQAFRAPTMGEMYNDAKHFSIGRFYTNYWVPNPNLRPETNETQEFGFGL
RFDDVMLANDALEFKASYFDTKAKDYISTSVDFAAATTMSMNVPHAKIWGWDVMAKYTAD
LFNLDVAYNRTRGKDTDTGEYISSINPDTVTSKLDIPVAQSGFSVGWIGTFVDRSTHISS
SYSEQPGYAVNDFYVSYKGQEQLKGVTTTLVLGNAFDKAYWSPQGIPQDGRNGKIFVSYQ
W