Protein Info for MPMX20_01800 in Enterobacter sp. TBS_079

Annotation: N-acetyl-D-glucosamine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00480: ROK
  • amino acids 2 to 300 (299 residues), 239.2 bits, E=7.4e-75
• PF02685: Glucokinase
  • amino acids 6 to 255 (250 residues), 31.2 bits, E=1.2e-11

Best Hits

Swiss-Prot: 85% identical to NAGK_ECOLI: N-acetyl-D-glucosamine kinase (nagK) from Escherichia coli (strain K12)

KEGG orthology group: K00884, N-acetylglucosamine kinase [EC: 2.7.1.59] (inferred from 95% identity to ent:Ent638_1634)

MetaCyc: 85% identical to N-acetyl-D-glucosamine kinase (Escherichia coli K-12 substr. MG1655)
N-acetylglucosamine kinase. [EC: 2.7.1.59]

Predicted SEED Role

"N-acetyl-D-glucosamine kinase (EC 2.7.1.59)" (EC 2.7.1.59)

MetaCyc Pathways

• N-acetylglucosamine degradation II (3/3 steps found)
• chitin derivatives degradation (4/8 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.59

Protein Sequence (303 amino acids)

>MPMX20_01800 N-acetyl-D-glucosamine kinase (Enterobacter sp. TBS_079)
MYYGFDIGGTKIALGVFDKNLKLQWETRVPTPRESYDEFLTAIAALVAQADSRFAVKGSV
GIGIPGMPETDDGTLYAANVPAASGKPLRADLSALLERDVRLDNDANCFALSEAWDDEFQ
RYPLVMGLILGTGVGGGIVTNGKPITGRSYITGEFGHIRLPVDALAVVGRDFPLTRCGCG
QHGCIENYLSGRGFAWLYEHFYHQKLEAPQIITLWEQGDAQAREHVERYLDLLAVCLGNI
LTIVDPDLLVIGGGLSNFSALTEQLSGRLPRHLLPVARVPRIERARHGDAGGMRGAAFLH
LTD