Protein Info for MPMX20_01797 in Enterobacter sp. TBS_079

Annotation: Lipoprotein-releasing system transmembrane protein LolC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 386 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 254 to 277 (24 residues), see Phobius details amino acids 297 to 323 (27 residues), see Phobius details amino acids 330 to 347 (18 residues), see Phobius details amino acids 352 to 371 (20 residues), see Phobius details TIGR02212: lipoprotein releasing system, transmembrane protein, LolC/E family" amino acids 1 to 386 (386 residues), 461.8 bits, see alignment E=1e-142 PF12704: MacB_PCD" amino acids 14 to 199 (186 residues), 56.3 bits, see alignment E=5.5e-19 PF02687: FtsX" amino acids 257 to 379 (123 residues), 62.1 bits, see alignment E=5.5e-21

Best Hits

Swiss-Prot: 93% identical to LOLC_ECOL6: Lipoprotein-releasing system transmembrane protein LolC (lolC) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K09808, lipoprotein-releasing system permease protein (inferred from 97% identity to enc:ECL_02520)

MetaCyc: 93% identical to lipoprotein release complex - inner membrane subunit (Escherichia coli K-12 substr. MG1655)
RXN-22427

Predicted SEED Role

"Lipoprotein releasing system transmembrane protein LolC"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (386 amino acids)

>MPMX20_01797 Lipoprotein-releasing system transmembrane protein LolC (Enterobacter sp. TBS_079)
MRGRAADRFGRFVSWLSTIGITLGVMALVTVLSVMNGFERELQNNILGLMPQAILSSTHG
SVNPQQLPESAAKLQGVTRVAPLTTGDVVLQSARSVAVGVMLGIDPAQNDPLTPFLVNVK
QTDLEAGKYNVILGEQLAGQLGVNRGDQLRVMVPSASQFTPMGRLPSQRLFTVVGTFAAN
SEVDGYQMLVNIQDASRLMRYPAGNITGWRLWLDAPLKVDTLSQQTLPEGTKWQDWRERK
GELFQAVRMEKNMMGLLLSLIVAVAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMAV
FMVQGASAGIIGALLGAALGALLASQLNNLMPIIGALLDGAALPVAIEPLQVIGIALAAM
AIALLSTLYPSWRAAATQPAEALRYE