Protein Info for MPMX20_01515 in Enterobacter sp. TBS_079

Annotation: Putative secretin GspD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 638 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF21305: type_II_gspD_N0" amino acids 29 to 98 (70 residues), 82.2 bits, see alignment E=3e-27 TIGR02517: type II secretion system protein D" amino acids 29 to 582 (554 residues), 533.9 bits, see alignment E=2.6e-164 PF03958: Secretin_N" amino acids 125 to 186 (62 residues), 42.7 bits, see alignment E=8.3e-15 amino acids 191 to 259 (69 residues), 46.1 bits, see alignment E=6.8e-16 amino acids 265 to 343 (79 residues), 57.8 bits, see alignment E=1.6e-19 PF00263: Secretin" amino acids 412 to 575 (164 residues), 171.8 bits, see alignment E=1.6e-54

Best Hits

Swiss-Prot: 59% identical to GSPD_ECOLI: Putative secretin GspD (gspD) from Escherichia coli (strain K12)

KEGG orthology group: K02453, general secretion pathway protein D (inferred from 93% identity to enc:ECL_02798)

MetaCyc: 59% identical to type II secretion system protein GspD (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"General secretion pathway protein D"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (638 amino acids)

>MPMX20_01515 Putative secretin GspD (Enterobacter sp. TBS_079)
MKKFPWACVALTALSLYSGSLLAANFSASFKNTDIREFIDTVGRNLNKTILVDPSVQGSV
SVRTYNVLTEDEYYQFFLSVLDLYGLSVIPMDNGMVKVVRSSVARTAGAPLADSTNPGKG
DEIITRVVRMENVPVRELAPLLRQLNDATGIGNVVHFEPSNVLLLTGKASVVNRLVDLVQ
RVDKDGVQRREIVPLRFASAKALSDMLNNLNNEEQKGQNAPQLATKVVADDETNSLVISG
SEDARTRTPSLIHELDREQNNEGNTRVFYLKYASATKVVPVLTGIGEQLKDKAGTAKAKT
ATAATDLNITADESTNSLVITAQPNVMNSLEKVIDKLDIRRPQVLVEAIIAEVQDGNGLD
LGVQWTGKHGGVQFGSTGLPISQIKNGTIKGASFTGLATGFFNGDFGALMTALSTDGKND
ILSTPSVVTLDNKEASFNVGQDVPVLSGSQTTSGDNVFNSVERKTVGTKLKIVPQINDGD
MIHLKIEQEVSSVDNSATEDASLGPTFNTRTINNEVMVHSGQTVVLGGLMENVTKQSVSK
VPLLGDIPLVGQLFRYTSQDASKRNLMVFIHTTVLRDDDNYSAASKEKYDQIRARQQQRV
EEKKLGIIEPADNAVLPAFPAASAASVKTSASRNPFKE