Protein Info for MPMX20_01486 in Enterobacter sp. TBS_079

Annotation: Arsenate reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00014: arsenate reductase (glutaredoxin)
  • amino acids 4 to 116 (113 residues), 137.9 bits, E=1.1e-44
• PF03960: ArsC
  • amino acids 7 to 114 (108 residues), 81 bits, E=6.3e-27

Best Hits

Swiss-Prot: 89% identical to ARSC1_ECOLX: Arsenate reductase (arsC) from Escherichia coli

KEGG orthology group: None (inferred from 91% identity to enc:ECL_02871)

MetaCyc: 89% identical to arsenate reductase (Escherichia coli)
Arsenate reductase (glutaredoxin). [EC: 1.20.4.1]

Predicted SEED Role

"Arsenate reductase (EC 1.20.4.1)" in subsystem Anaerobic respiratory reductases or Arsenic resistance (EC 1.20.4.1)

MetaCyc Pathways

• arsenic detoxification (bacteria) (4/4 steps found)
• arsenate detoxification I (5/6 steps found)
• arsenic detoxification (plants) (5/6 steps found)
• arsenate detoxification III (2/2 steps found)
• arsenic detoxification (yeast) (4/12 steps found)

Isozymes

Compare fitness of predicted isozymes for: 1.20.4.1

Use Curated BLAST to search for 1.20.4.1

Protein Sequence (143 amino acids)

>MPMX20_01486 Arsenate reductase (Enterobacter sp. TBS_079)
MSHITIYHNPACGTSRNTLEMIRNSGTEPEIILYLENPPSRDELTRLIAEMGISVRDLLR
KNVEPYEQLGLAGDRFTDDQLIDSMLQHPILINRPIVVTPLGTRLCRPSEVVLDILPDAQ
KGAFTKEDGEAVVDASGKKISGS