Protein Info for MPMX20_01251 in Enterobacter sp. TBS_079

Annotation: Proofreading thioesterase EntH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 137 TIGR00369: uncharacterized domain 1" amino acids 20 to 133 (114 residues), 150.2 bits, see alignment E=1.3e-48 PF03061: 4HBT" amino acids 50 to 127 (78 residues), 68.8 bits, see alignment E=2.1e-23

Best Hits

Swiss-Prot: 89% identical to ENTH_ENTLS: Proofreading thioesterase EntH (entH) from Enterobacter lignolyticus (strain SCF1)

KEGG orthology group: None (inferred from 93% identity to ent:Ent638_1129)

MetaCyc: 87% identical to proofreading thioesterase in enterobactin biosynthesis (Escherichia coli K-12 substr. MG1655)
3.1.2.-

Predicted SEED Role

"Proofreading thioesterase in enterobactin biosynthesis EntH" in subsystem Siderophore Enterobactin

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (137 amino acids)

>MPMX20_01251 Proofreading thioesterase EntH (Enterobacter sp. TBS_079)
MIWKRHLSREEMNATSLNSMVAHLGIVYTRIGDDTLEAEMPVDARTHQPFGLLHGGASAA
LAETLGSMAGFLMTRDGQSVVGTELNATHHRAVSHGKVRGVCQPLHLGRTSQSWEIVVFD
EQGRRCCTCRLSTQILG