Protein Info for MPMX20_01233 in Enterobacter sp. TBS_079

Annotation: Leukotoxin export ATP-binding protein LtxB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 710 transmembrane" amino acids 179 to 200 (22 residues), see Phobius details amino acids 207 to 230 (24 residues), see Phobius details amino acids 239 to 258 (20 residues), see Phobius details amino acids 287 to 331 (45 residues), see Phobius details amino acids 397 to 417 (21 residues), see Phobius details PF03412: Peptidase_C39" amino acids 21 to 149 (129 residues), 141.6 bits, see alignment E=2.8e-45 PF00664: ABC_membrane" amino acids 179 to 442 (264 residues), 136.1 bits, see alignment E=3.9e-43 PF00005: ABC_tran" amino acids 510 to 658 (149 residues), 111.5 bits, see alignment E=1e-35

Best Hits

Swiss-Prot: 68% identical to MCHF_ECOLX: Probable microcin-H47 secretion/processing ATP-binding protein MchF (mchF) from Escherichia coli

KEGG orthology group: None (inferred from 75% identity to srr:SerAS9_0072)

Predicted SEED Role

"Putative secretion ATPase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (710 amino acids)

>MPMX20_01233 Leukotoxin export ATP-binding protein LtxB (Enterobacter sp. TBS_079)
MSKRAFKTLLGQLDLHLRSRVPLVHQTESSECGLACLAMICNHYGKNSNLISLRQQFNLS
ARGTTLAGMKEIAEQLGLTSRCLSLELHELNSLKIPCILHWDFNHFVVLVGVKQNRVILH
DPARGRRTINLEEMSQYFTGIALEVWPGSTFTEEQESHHFSLKALAAKVHGLKGTLAKIF
FYSLIIESINLLIPIGTQLALDHAIPAADVGLLTLICIGLLLFTFLRLALSALRSWSSLL
MTTLINVQWQSGLFSHLLRLPLSYFERRKLGDIQSRFGSLNTLRETFTSSIVGALIDGTM
LIGVVIMMALYGGWLTGVVMCFTALYVLIRLMTYSTYRELSEEILVRDARTRSYFMETLY
GIATIKMQGFSERRSIHWLNLEIDTINTEIKITKMDLLFGGVNSLITACEQIAMLWLGSR
LIIDNDITIGMFIAFGVFREQFADRIWSLTNFLTKLRMMHLHNERVADIALNTQEKKKPD
REILNTMKPVALEINALSYRYDDHSAAVFRGLSFQVLAGESVAITGPSGAGKTTLMRVLC
GLFEPQTGSVMIDGNDIQQLGLNNYRKIIGCVMQDDKLFSGSIRENICGFDENADYEWME
ECARASFIHGAIVKMPMGYDTLVGELGEGLSGGQKQRIFIARALYRKPGILFMDEATSAL
DEESETYVNQAIKKLNITRIIIAHRQSTIASVERVIRLMPQTEQHGLHSE