Protein Info for MPMX20_01223 in Enterobacter sp. TBS_079

Annotation: Alpha-acetolactate decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 TIGR01252: alpha-acetolactate decarboxylase" amino acids 29 to 257 (229 residues), 292.8 bits, see alignment E=8.2e-92 PF03306: AAL_decarboxy" amino acids 30 to 247 (218 residues), 279.9 bits, see alignment E=6.1e-88

Best Hits

Swiss-Prot: 99% identical to ALDC_KLEAE: Alpha-acetolactate decarboxylase (budA) from Klebsiella aerogenes

KEGG orthology group: K01575, acetolactate decarboxylase [EC: 4.1.1.5] (inferred from 95% identity to ent:Ent638_2026)

MetaCyc: 99% identical to alpha-acetolactate decarboxylase (Klebsiella aerogenes)
Acetolactate decarboxylase. [EC: 4.1.1.5]

Predicted SEED Role

"Alpha-acetolactate decarboxylase (EC 4.1.1.5)" in subsystem Acetoin, butanediol metabolism or Alpha-acetolactate operon (EC 4.1.1.5)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (260 amino acids)

>MPMX20_01223 Alpha-acetolactate decarboxylase (Enterobacter sp. TBS_079)
MMVHSSACDCEASLCETLRGFSAQHPDSVIYQTSLMSALLSGVYEGDTTIADLLAHGDFG
LGTFNELDGEMIAFSSQVYQLRADGSARAAKPEQKTPFAVMTWFQPQYRKTFDAPVSRQQ
IHDVIDQQIPSDNLFCALRIDGNFRHAHTRTVPRQKPPYRAMTDVLDDQPVFRFNQREGV
LVGFRTPQHMQGINVAGYHEHFITDDRQGGGHLLDYQLESGVLTFGEIHKLMIDLPADSA
FLQANLHPSNLDAAIRSVEN