Protein Info for MPMX20_01137 in Enterobacter sp. TBS_079

Annotation: Multiple antibiotic resistance protein MarA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 113 PF00165: HTH_AraC" amino acids 15 to 56 (42 residues), 34.8 bits, see alignment E=1.4e-12 amino acids 70 to 106 (37 residues), 26.9 bits, see alignment E=4.1e-10 PF12833: HTH_18" amino acids 28 to 106 (79 residues), 80.2 bits, see alignment E=1.2e-26

Best Hits

Swiss-Prot: 96% identical to RAMA_ENTCL: Transcriptional activator RamA (ramA) from Enterobacter cloacae

KEGG orthology group: None (inferred from 97% identity to ent:Ent638_1078)

Predicted SEED Role

"Transcriptional activator RamA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (113 amino acids)

>MPMX20_01137 Multiple antibiotic resistance protein MarA (Enterobacter sp. TBS_079)
MTISAQVIDTIVEWIDDNLHQPLRIEEIARHAGYSKWHLQRLFMQYKGESLGRYIRERKL
LLAARDLRESDERVYDICLRYGFDSQQTFTRIFTRTFNQPPGAYRKENHSRTH