Protein Info for MPMX20_01052 in Enterobacter sp. TBS_079

Annotation: Beta-galactosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1030 PF02837: Glyco_hydro_2_N" amino acids 56 to 220 (165 residues), 216.6 bits, see alignment E=5.4e-68 PF00703: Glyco_hydro_2" amino acids 222 to 335 (114 residues), 53.6 bits, see alignment E=9e-18 PF02836: Glyco_hydro_2_C" amino acids 337 to 629 (293 residues), 397.1 bits, see alignment E=1.2e-122 PF16353: LacZ_4" amino acids 641 to 728 (88 residues), 75.9 bits, see alignment E=6.4e-25 PF02929: Bgal_small_N" amino acids 757 to 1024 (268 residues), 196.8 bits, see alignment E=1.3e-61

Best Hits

Swiss-Prot: 86% identical to BGAL2_ENTCL: Beta-galactosidase 2 (lacZ) from Enterobacter cloacae

KEGG orthology group: K01190, beta-galactosidase [EC: 3.2.1.23] (inferred from 87% identity to enc:ECL_01221)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1030 amino acids)

>MPMX20_01052 Beta-galactosidase (Enterobacter sp. TBS_079)
MSNTPSLTLSALLARRDWENPGVTQWNRLAAHAPLHSWRDEHSAREDGGTVSRRLLNGEW
RFSFFPAPEQVPSVWVGEDCADAVLMPVPSNWQMQGFDTPIYTNVTYPIPVNPPFVPQEN
PTGCYSLTFEMDDAWLQSGQTRIIFDGVNSAFHLWCNGRWIGYSQDSRLPAEFDLSAVLR
PGENRIAVMVLRWCDGSYLEDQDMWRMSGIFRDVSLLHKPETHIADYQVVTDLNAERDRA
VLKVDLALAGAQFAECEVAFTLWRNGEKCASATGRPGTAAVDERGGWAERLTVTLPVEAP
ALWSAETPELYRLTMTLLNAQGELLETEACDVGFRRIEISNGLLKLNGKPLLIRGVNRHE
HHPENGQVMDEATMRRDIELMKQHNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETH
GMVPMSRLADDPRWLPAMSERVTRMVQRDRNHPSIIIWSLGNESGHGANHDALYRWLKTT
DPTRPVQYEGGGANTAATDIVCPMYARVDQDQPFPAVPKWSVKKWIGMPDETRPLILCEY
AHAMGNSFGGFAKYWQAFRRHPRLQGGFVWDWVDQALTRKDENGTPFWAYGGDFGDTPND
RQFCLNGLVFPDRTPHPALYEAQRAQQFFTFTRVSTSPLVLEVHSDYLFRHTDNEVLRWT
LVRDGSVLARGDVTLSIAPQGTQRLDINLPALAPEAGDVWLNVEVHQPRATPWSPANHRC
AWEQWPVPTPLYIAPPAPEGVPPVLTQTGDVFELVHQQQRWQFNRASGHLTQWWRNGVET
LLSPLTDNVSRAPLDNDIGVSEATRIDPNAWVERWKAAGMYELTPRLLHCEGEQHAAEAV
VKTLHVWEYRGKALFLSRKVWRVDDRGVLHGDIQVDIASDIPEPARVGLSVHLAATPETV
QWLGLGPHENYPDRTLAAQQGRWTLPLEAMHTPYIFPTENGLRCDTRELLLGAHRLNGLF
HFSVSRYSQQQLHETTHHHLLREEPGCWLNLDAFHMGVGGDDSWSPSVSPEFILQKRQLR
YTFSWQQNPD