Protein Info for MPMX20_01027 in Enterobacter sp. TBS_079

Annotation: Trigger factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 PF05697: Trigger_N" amino acids 1 to 143 (143 residues), 152.9 bits, see alignment E=1.2e-48 TIGR00115: trigger factor" amino acids 13 to 412 (400 residues), 473.3 bits, see alignment E=3.2e-146 PF00254: FKBP_C" amino acids 158 to 237 (80 residues), 64.3 bits, see alignment E=1.6e-21 PF05698: Trigger_C" amino acids 262 to 412 (151 residues), 142 bits, see alignment E=2.8e-45

Best Hits

Swiss-Prot: 97% identical to TIG_ENT38: Trigger factor (tig) from Enterobacter sp. (strain 638)

KEGG orthology group: K03545, trigger factor (inferred from 99% identity to enc:ECL_01194)

MetaCyc: 93% identical to trigger factor (Escherichia coli K-12 substr. MG1655)
Peptidylprolyl isomerase. [EC: 5.2.1.8]

Predicted SEED Role

"Cell division trigger factor (EC 5.2.1.8)" in subsystem Bacterial Cell Division (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (432 amino acids)

>MPMX20_01027 Trigger factor (Enterobacter sp. TBS_079)
MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNVVAQRYGA
SVRQDVLGELMSRNFIDAIIKEKINPAGAPNYVPGEYKQGEDFTYSVEFEVYPEVELKGL
ESIEVEKPVVSVTDEDVDGMLDTLRKQQANWKEKEGAVDAEDRVTIDFTGSVDGEEFEGG
KASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFVINLKKV
EERELPELTEEFIKRFGVEDGSVAGLRTEVRKNMERELNGAVRNRVKSQAIDGLVKANEI
DVPAALIDSEIDVLRRQAAQRFGGNQQQAMELPRELFEEQAKRRVVVGLLLGEVIRTHEL
KADEERVKGLIEEMASAYEDPSEVIEFYGKNKELMDNMRNVALEEQAVEAVLAKAKVTEK
ATSFNELMNQQA