Protein Info for MPMX20_00763 in Enterobacter sp. TBS_079

Annotation: HTH-type transcriptional regulator SgrR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 551 PF12793: SgrR_N" amino acids 5 to 118 (114 residues), 145.3 bits, see alignment E=9.6e-47 PF00496: SBP_bac_5" amino acids 165 to 308 (144 residues), 60.9 bits, see alignment E=1.3e-20

Best Hits

Swiss-Prot: 81% identical to SGRR_SALTI: HTH-type transcriptional regulator SgrR (sgrR) from Salmonella typhi

KEGG orthology group: K11925, SgrR family transcriptional regulator (inferred from 94% identity to enc:ECL_00865)

Predicted SEED Role

"SgrR, sugar-phosphate stress, transcriptional activator of SgrS small RNA" in subsystem Sugar-phosphate stress regulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (551 amino acids)

>MPMX20_00763 HTH-type transcriptional regulator SgrR (Enterobacter sp. TBS_079)
MPSGRLQQQFIRLWQCCEGRSQETTLNELADLLSCSRRHMRTLLNTMQKQGWLNWEAEAG
RGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAAVRQMLVSHLGRSFRQGRH
ILRVLYYRPMKNLLPGTALRRSETHMARQIFSGLTRINEENGELEADIAHHWQQLSPLHW
RFFLRPGIHFHHGRELEMVDVIASLERACTLPLYSHISRVHSPTAWTLDVELSQPDKWLP
WLLGYVPSMILPGEWESMNNFASLPIGTGPYSVSRNNNNQLKIRAFDDYFGYRALIDEVN
VWVLPDLNEELSAGLTLEGPTTGEKAVESRLEEGCYYLLFDSRTHRGANHEVRKWISHVL
SPSSLIYHAEEQYQTYWFPAYGLLPRWHHARPTYCDKPAGLESITLTYYREHVEHRFIAR
IMTRLLAAVGVRLDVKEVDYDEWHQGEIVSDIWLNSANFTLPLDFSLFSHLYEVPLIQHC
IDRDWQQDAALWRAGDMNLASWCQQLLAEQAIVPLIHHWLMIQGQRSMRGVRMNTLGWFD
FKSAWFSPPEP