Protein Info for MPMX20_00548 in Enterobacter sp. TBS_079
Annotation: Carbamate kinase 1
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 56% identical to ARCC_PSEAE: Carbamate kinase (arcC) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG orthology group: K00926, carbamate kinase [EC: 2.7.2.2] (inferred from 96% identity to enc:ECL_00670)MetaCyc: 43% identical to carbamate kinase subunit (Giardia intestinalis)
Carbamate kinase. [EC: 2.7.2.2]
Predicted SEED Role
"Carbamate kinase (EC 2.7.2.2)" in subsystem Arginine Deiminase Pathway or Arginine and Ornithine Degradation or MLST or Polyamine Metabolism (EC 2.7.2.2)
MetaCyc Pathways
- L-arginine degradation V (arginine deiminase pathway) (4/4 steps found)
- L-citrulline degradation (3/3 steps found)
- allantoin degradation IV (anaerobic) (3/9 steps found)
- guadinomine B biosynthesis (2/13 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.7.2.2
Use Curated BLAST to search for 2.7.2.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (303 amino acids)
>MPMX20_00548 Carbamate kinase 1 (Enterobacter sp. TBS_079) MERKPTLVVALGGNALLKRGEPLEAEIQRQNIELAARTIAGLTEQWRVVLVHGNGPQVGL LALQNSAYDKVTPYPLDILGAESQGMIGYMLQQALKNNLPQREVSVLLTQVEVDAADPAF TNPTKYIGPVYSEAQAKTLQAEKGWVFKADGSYFRRVVPSPQPKRIVESDAITALIQRDH LVICNGGGGVPVVENANGYHGIEAVIDKDLSAALLARQIEADALLILTDADAVYLDWGKP TQRPLAQVTPELLRGMQFDAGSMGPKVAACREFVEACNGIAGIGALADGADILAGEKGTL IRH