Protein Info for MMP_RS08655 in Methanococcus maripaludis S2
Annotation: phosphoadenosine phosphosulfate reductase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 58% identical to Y973_METJA: Uncharacterized protein MJ0973 (MJ0973) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
KEGG orthology group: None (inferred from 100% identity to mmp:MMP1681)Predicted SEED Role
"PUA-PAPS reductase like fusion"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (archaea)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q6LWM8 at UniProt or InterPro
Protein Sequence (428 amino acids)
>MMP_RS08655 phosphoadenosine phosphosulfate reductase family protein (Methanococcus maripaludis S2) MFNEDTKFASPYEINVLNELTGKNFQEDDLILLEKLSGMDYRKRVYVSEDQIGTLEFDLL DLTWKFIPSPLYYMIEDPKISLKYTKKRLKGKYIKEELLENPEELNEALKDNFEYIGVKI GDFLGVGVRKEDRVKVKDLSRKKELDFQKIADYLEYNKEYLDEMVENSIEILQDAVEKYK RKGYAINASFSGGKDSAVCTLISKEVIPDLDVVFIDTGLEYPETLNYVKDFVDKYDINLD TVDGDNFWDNLEKEGIPTKDNRWCNSACKLMPLKRYLKKKYGNKKVLTIDGSRKYESFTR ANLDYERRSGFIDFQTNVFPILDWNSIDIWSYIYSKDIPYNPMYDKGFERIGCYLCPSAL NSEFLRVKELHPDYFERWVKYLKKYFPESEVLRGFWRWDELPPKMVELEENMGVDIDKKK RLKRITQL