Protein Info for MMP_RS08635 in Methanococcus maripaludis S2

Annotation: UbiA family prenyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 278 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 40 to 60 (21 residues), see Phobius details amino acids 87 to 115 (29 residues), see Phobius details amino acids 136 to 166 (31 residues), see Phobius details amino acids 199 to 218 (20 residues), see Phobius details amino acids 224 to 246 (23 residues), see Phobius details amino acids 258 to 277 (20 residues), see Phobius details PF01040: UbiA" amino acids 22 to 257 (236 residues), 134.8 bits, see alignment E=1.7e-43

Best Hits

Swiss-Prot: 100% identical to DGGGP_METMP: Digeranylgeranylglyceryl phosphate synthase (MMP1677) from Methanococcus maripaludis (strain S2 / LL)

KEGG orthology group: K03179, 4-hydroxybenzoate octaprenyltransferase [EC: 2.5.1.-] (inferred from 100% identity to mmp:MMP1677)

Predicted SEED Role

"(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase" in subsystem Archaeal lipids

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.5.1.-

Use Curated BLAST to search for 2.5.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LWN2 at UniProt or InterPro

Protein Sequence (278 amino acids)

>MMP_RS08635 UbiA family prenyltransferase (Methanococcus maripaludis S2)
MDIKAYFELIRLKNCLTASFGAFIGGLIASYFNLAMVDNLILASIVVFLVCGFGNALNDI
YDLKIDRINKPKRPIPSKRITLNNAKVFSYSLVVMGLFISLFNISCFLMAVLNSIVLQQY
ASTYKKNKIIGNLIVAYLTGSVFIFGGIAVGNIDVTIMLFLCALFAMWSREIIKDYEDIE
GDLKEKVISIPIKCGERSIYIAAFLLIFAIFLSPLPYLFGFFGIYYMISVVFCDLLFLFG
IYKLVFNPSKMEAKKASRNIKIVTNLVLIAFLIGSLFK