Protein Info for MMP_RS08605 in Methanococcus maripaludis S2

Annotation: flagellar protein E

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 135 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF04659: Arch_fla_DE" amino acids 15 to 107 (93 residues), 93.1 bits, see alignment E=4.1e-31

Best Hits

Swiss-Prot: 79% identical to FLAE_METVO: Putative flagella-related protein E (flaE) from Methanococcus voltae

KEGG orthology group: K07328, archaeal flagellar protein FlaE (inferred from 98% identity to mmz:MmarC7_0944)

Predicted SEED Role

"Flagella-related protein FlaE" in subsystem Archaeal Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LWN8 at UniProt or InterPro

Protein Sequence (135 amino acids)

>MMP_RS08605 flagellar protein E (Methanococcus maripaludis S2)
MNTAALSSILLESQKPAKLEAVPEDAFSLIFAFKWLEYLSERVGQSNIADILEFYYNLGW
LSDNAISGLLKFSKGIKIEDDDIASPSGKLTIADHLVSLLFIERLNGKKISSEVLDKLEW
EIRRIKRGAEQYYGI