Protein Info for MMP_RS08535 in Methanococcus maripaludis S2
Annotation: bis-aminopropyl spermidine synthase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 60% identical to Y675_METJA: Uncharacterized protein MJ0675 (MJ0675) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
KEGG orthology group: K07057, (no description) (inferred from 100% identity to mmp:MMP1657)Predicted SEED Role
"Predicted methyltransferase, DUF43 family"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (archaea)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q6LWQ1 at UniProt or InterPro
Protein Sequence (390 amino acids)
>MMP_RS08535 bis-aminopropyl spermidine synthase family protein (Methanococcus maripaludis S2) MKIIGSMGKKTENLKIDAKKSFLKRIAKNVKVSEGERAVEDILRCIYRNQPISTKKIGQY VKLPLPIVSKVRSILERESLLKRDDKGAVLSKKGIDFVENELGLKLKSDMKCPVCSGRNI VFDEKFEKILKKHKTYAKLRPQVNTMIDQSFATPETATARAAIMADRGDLEGKRVLFVGD DDLASIPTAMTGLCSEVVVLDIDDRLLKLISEVSKKENLNIRTVKWDFKNELPSEFVNKF DTIFTDPPYTLNGAVLFMSRGIEALGDNGILYLAFSHKPVEEYIELQKSINNMNFLIYEL IPGFNFYEGTEIIGNTTFLARLVGKNLKKIEVNSEKIYTGELKPTLRYYQCMNCKKIHEV GNKVKRIEDLTCECGGKKFSMIKRAKVKQK