Protein Info for MMP_RS07770 in Methanococcus maripaludis S2

Annotation: alanine racemase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 TIGR00492: alanine racemase" amino acids 6 to 372 (367 residues), 426.7 bits, see alignment E=3.5e-132 PF01168: Ala_racemase_N" amino acids 10 to 231 (222 residues), 270.5 bits, see alignment E=1.2e-84 PF00842: Ala_racemase_C" amino acids 245 to 371 (127 residues), 162.7 bits, see alignment E=3.2e-52

Best Hits

Swiss-Prot: 100% identical to ALR_METMP: Alanine racemase (alr) from Methanococcus maripaludis (strain S2 / LL)

KEGG orthology group: K01775, alanine racemase [EC: 5.1.1.1] (inferred from 100% identity to mmp:MMP1512)

Predicted SEED Role

"Alanine racemase (EC 5.1.1.1)" in subsystem Alanine biosynthesis or Pyruvate Alanine Serine Interconversions (EC 5.1.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LX41 at UniProt or InterPro

Protein Sequence (373 amino acids)

>MMP_RS07770 alanine racemase (Methanococcus maripaludis S2)
MVSHPIWAEIDLSAIKNNIKEIRRITNPKSQVMAVVKANAYGHGSVEVSKICLENGADRL
AVARSTEALELRDAGITCPILVFGYVTEEEILKMVENDITLTVYSLEIANSIQKIAEKLG
KHSKIHIKVDTGMSRLGFLPEKSSVETIKKIRELENIEVEGIYTHFADADNSDKTYTTMQ
FSKFTSFLHDLEENGIDIPIKHASNSAAIIDHPETHLNMVRPGIILYGLYPSELVHKERI
NLQPAMSLKVLVTHVKDVPENTKISYGCTFETKKQSKIASLPIGYADGFTRMLRNGNVLI
HGLRVPVVGRICMDQCMIDVTSIENVNVGDVVTVFGKDGTEKISIEEFGNKLGTINYELV
CMVSARVPRIYLH