Protein Info for MMP_RS07680 in Methanococcus maripaludis S2

Annotation: DUF366 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 PF04017: DUF366" amino acids 11 to 196 (186 residues), 238 bits, see alignment E=2.7e-75

Best Hits

Swiss-Prot: 63% identical to Y805_METJA: Uncharacterized protein MJ0805 (MJ0805) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K09139, hypothetical protein (inferred from 100% identity to mmp:MMP1494)

Predicted SEED Role

"Archaeosine cluster gene X"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LX58 at UniProt or InterPro

Protein Sequence (200 amino acids)

>MMP_RS07680 DUF366 family protein (Methanococcus maripaludis S2)
MKKIDFDTISAVILEEFKTYTGKEIEPLWAFNTFDVQKDSIVGFIGPMNVKIENMKDLKD
VKEEKDVEIPIQSSEAINFIVEHFDNPDLKMTYLRQRILVSTAKEVIENHGNLKLKKSGD
DLYFNDKKLSVCIACRGISSGKIHLGINIKSGGVPPYVSAVGLNDMGIENTFEIMEEIAS
IYAKEMSKIEKDIRKTLPLF