Protein Info for MMP_RS07530 in Methanococcus maripaludis S2

Annotation: 4Fe-4S binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 161 PF13237: Fer4_10" amino acids 30 to 78 (49 residues), 28.6 bits, see alignment E=7.1e-10 amino acids 109 to 154 (46 residues), 33.6 bits, see alignment E=1.9e-11 PF12837: Fer4_6" amino acids 30 to 52 (23 residues), 26.5 bits, see alignment 2.7e-09 amino acids 136 to 158 (23 residues), 29.2 bits, see alignment 3.9e-10 PF00037: Fer4" amino acids 31 to 54 (24 residues), 27.8 bits, see alignment 9.8e-10 amino acids 64 to 83 (20 residues), 27.8 bits, see alignment (E = 9.8e-10) amino acids 109 to 130 (22 residues), 23.3 bits, see alignment (E = 2.6e-08) amino acids 137 to 159 (23 residues), 30.5 bits, see alignment 1.4e-10 PF12800: Fer4_4" amino acids 35 to 50 (16 residues), 14.4 bits, see alignment (E = 2.5e-05) amino acids 65 to 79 (15 residues), 12.5 bits, see alignment (E = 0.0001) amino acids 141 to 155 (15 residues), 13.1 bits, see alignment (E = 6.8e-05) PF12798: Fer4_3" amino acids 38 to 52 (15 residues), 16.8 bits, see alignment (E = 5.8e-06) amino acids 67 to 81 (15 residues), 15.6 bits, see alignment (E = 1.4e-05) amino acids 143 to 157 (15 residues), 14.2 bits, see alignment (E = 4e-05) PF13187: Fer4_9" amino acids 38 to 82 (45 residues), 29.4 bits, see alignment E=4.1e-10 amino acids 113 to 158 (46 residues), 34.5 bits, see alignment E=1e-11 PF12838: Fer4_7" amino acids 66 to 128 (63 residues), 39 bits, see alignment E=5.5e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP1464)

Predicted SEED Role

"Energy conserving hydrogenase Eha ferredoxin (protein P2)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LX88 at UniProt or InterPro

Protein Sequence (161 amino acids)

>MMP_RS07530 4Fe-4S binding protein (Methanococcus maripaludis S2)
MIDMVSKILKKYFDNLDINFELDSQYISNKIEINPEICILCNRCLEVCPVTAISSNFPEV
PDIDNKCVYCNTCVETCPVDAIKITKTRVRVENGNLIIENRLKSKKLDYNRKKCVMCLVC
TKNCPFEAISESDDTISFNMDKCVLCGHCEEICPAKAIKLE