Protein Info for MMP_RS07330 in Methanococcus maripaludis S2

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 852 transmembrane" amino acids 20 to 36 (17 residues), see Phobius details amino acids 111 to 128 (18 residues), see Phobius details amino acids 140 to 160 (21 residues), see Phobius details amino acids 167 to 185 (19 residues), see Phobius details amino acids 192 to 210 (19 residues), see Phobius details amino acids 222 to 238 (17 residues), see Phobius details amino acids 244 to 263 (20 residues), see Phobius details amino acids 275 to 300 (26 residues), see Phobius details amino acids 342 to 361 (20 residues), see Phobius details amino acids 370 to 387 (18 residues), see Phobius details amino acids 393 to 413 (21 residues), see Phobius details amino acids 425 to 443 (19 residues), see Phobius details amino acids 455 to 476 (22 residues), see Phobius details amino acids 488 to 510 (23 residues), see Phobius details PF02516: STT3" amino acids 29 to 439 (411 residues), 203.6 bits, see alignment E=8e-64 PF21436: STT3-PglB_core" amino acids 533 to 680 (148 residues), 25.8 bits, see alignment E=1.3e-09

Best Hits

KEGG orthology group: K07151, dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC: 2.4.1.119] (inferred from 100% identity to mmp:MMP1424)

Predicted SEED Role

"Oligosaccharyltransferase PglB (EC 2.4.1.119)" in subsystem N-linked Glycosylation in Bacteria (EC 2.4.1.119)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.119

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LXC8 at UniProt or InterPro

Protein Sequence (852 amino acids)

>MMP_RS07330 membrane protein (Methanococcus maripaludis S2)
MGEFLNKVSDFFKKNEKIKIILILLFIGMMSFQIRAQTADMAFTDNSYLQDMFSDDNGRM
YLTALDPYYYLRMTENYVNNDYSNVGETTVGIDGENIPYDTIQYAPPGREAGLVSALSIA
TVLVYSVWNSIDSTVTIMNAAFWVPAIMSIFLGIPVFFIVRRNTASNIGGLVGALLLISS
PSLLYKTSAGFSDTPIFEILPLLFIVWMIMEAIHEQENSKKSGIFGGIAAILIGLYPMMW
SGWWYAFDITAGFLVLYTAYEYLTKSKNLKNVITTSLITLVGGAILVSLSTGLSGFINWI
LSPIGFTVINEATKITGWPNVYMTVSELAIPTVTDIIENSVGNIWLLIAGISGILLSFVS
FKHDKQKIDIKYALYLTLWLIATVYAATKGIRFVALMTPALAIGIGIFAGQIENIIKRYE
KKVEYILYPVIGILSVITLIKYGGELFNILVPTTYVPIAVYLSIIALLVLAVYKIIDIIS
EKEQAVKKVFGILLAFMLVFPSMAAAVPFYTAPTMNNGWMDSLSWIKSETPENSVVTCWW
DNGHIYTWATRKMVTFDGGSQNTPRAYWVGHAFSTSDENLSVGILRMLATSGDSAYDDDS
ILIKKTGSIKDTVDILNKILPLTRTEAKASLVNNYDLTDAEAEEVLDLTHPKVTNPDYLI
TYNRMTSIASVWSMFGNWNFSLPASTENSDREMGYYQQLGGSAQDINGTTVVYIPLQETD
SYRVINILEITDSEIKSANAVIDSNNQTSMQSPNFHKLILKVNGNVYEQETNENGDYSEI
VRLEKLSDGTYQVYAWVSSKNLEDSIYTKLHFLDGYGLEKISLEKESVDPTSYGIQPGFK
VYSVDYGTDYLN