Protein Info for MMP_RS06665 in Methanococcus maripaludis S2

Annotation: glycogen/starch synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 522 PF08323: Glyco_transf_5" amino acids 2 to 195 (194 residues), 108 bits, see alignment E=1.3e-34 PF00534: Glycos_transf_1" amino acids 297 to 418 (122 residues), 72.9 bits, see alignment E=5e-24 PF13692: Glyco_trans_1_4" amino acids 301 to 414 (114 residues), 64.4 bits, see alignment E=2.8e-21

Best Hits

Swiss-Prot: 57% identical to GLGA_METJA: Probable glycogen synthase (glgA) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K00703, starch synthase [EC: 2.4.1.21] (inferred from 100% identity to mmp:MMP1294)

Predicted SEED Role

"Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)" in subsystem Glycogen metabolism (EC 2.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LXQ5 at UniProt or InterPro

Protein Sequence (522 amino acids)

>MMP_RS06665 glycogen/starch synthase (Methanococcus maripaludis S2)
MKIVTLTPTIAPLTSIGGLGDILEDLPKFLKNLGNEVYVITYDHQNKISKRPHEIIKKIE
VKYQGSKLFFDVIKAVHPSSNFEIFAFSNPEINQLDSWDPIKYEIFADLVVSFLSDIENI
ECVSGHDWPCGLAIAKCHEKLNLPTTLTIHNEAFKGPIIEYKGHIFSFLEHGIYFSDAVN
TVSPNHAEEIRNLDFLKKLCKEKPFHGIINGIDTDVYSPESIIERMKNLSNGKLNPQDYC
YIENYDISNAAVVKPKIKESWFCKCENLKKYINDWNEMDKSNISGSDIEIHGNIKGKLKT
PMIGFVGRATYQKGFDLIFETMPEVLEENNANFVLVSKGEKSIEEKIKDFAESYPDKIMA
LVGHCPPIIPIIYAGCDWTVVPSLWEPCGLTQMESMSYGTPVIARNTGGLSDTVISLHPD
PHKNPNFDIATGVLFNDYDKYGFKWGIEHGLYWSFYNLEEACLFINYKHVHCPESPYEEN
SPLYMLIKNCYHHVQKNLSWQNNDSSERYRALFGGAMYKHYF