Protein Info for MMP_RS06660 in Methanococcus maripaludis S2

Annotation: glycosyltransferase family 4 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 PF08323: Glyco_transf_5" amino acids 2 to 165 (164 residues), 76.6 bits, see alignment E=1e-24 PF13439: Glyco_transf_4" amino acids 15 to 183 (169 residues), 102.4 bits, see alignment E=1.2e-32 PF20706: GT4-conflict" amino acids 16 to 330 (315 residues), 50.5 bits, see alignment E=6.4e-17 PF13579: Glyco_trans_4_4" amino acids 16 to 180 (165 residues), 64.6 bits, see alignment E=5.6e-21 PF13477: Glyco_trans_4_2" amino acids 20 to 122 (103 residues), 25 bits, see alignment E=8.2e-09 PF00534: Glycos_transf_1" amino acids 197 to 363 (167 residues), 161.4 bits, see alignment E=6.1e-51 PF13692: Glyco_trans_1_4" amino acids 209 to 350 (142 residues), 108 bits, see alignment E=2e-34 PF13524: Glyco_trans_1_2" amino acids 291 to 379 (89 residues), 28.7 bits, see alignment E=4.9e-10

Best Hits

Swiss-Prot: 68% identical to Y1607_METJA: Uncharacterized glycosyltransferase MJ1607 (MJ1607) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP1293)

Predicted SEED Role

"Glycosyltransferase (EC 2.4.1.-)" (EC 2.4.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.-

Use Curated BLAST to search for 2.4.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LXQ6 at UniProt or InterPro

Protein Sequence (391 amino acids)

>MMP_RS06660 glycosyltransferase family 4 protein (Methanococcus maripaludis S2)
MKVSIVTWEYHPVMVGGLAVHCKGLSEALVRAGNEVDVITVGYDLPEYEEINGVNVYRVK
PISHNNFLTWAMFMASSFEKKIGSLGVENYDVIHCHDWMTSFVGSNIKHTTKKPYVQSIH
STERGRCGGINSEDSRAINDAEWWGSYEANQLIAVSHSIKDEMCFGFNTPWEKVNVIYNG
VNPWEFDINCDDNEKYNFRRNLGITDNENMILYVGRLVYQKGVEHLIRGFQKFLIGHPNS
KLVIAGEGHMQGHLEHLAWVLGCGDRVIFLGFKNGNFLKKLYKYADACVIPSVYEPFGIV
ALESMAAGTPVVASDVGGLSEIINHEYNGVKVYPRDADSIAWGLDRVISDRGFREWIVKN
AKHDAYTKYSWDAIANQTIQVYKRAIEMMKQ