Protein Info for MMP_RS06655 in Methanococcus maripaludis S2

Annotation: glycoside hydrolase family 15 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 621 transmembrane" amino acids 532 to 550 (19 residues), see Phobius details PF00723: Glyco_hydro_15" amino acids 269 to 612 (344 residues), 97.4 bits, see alignment E=4.5e-32

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP1292)

Predicted SEED Role

"Glucoamylase (EC 3.2.1.3)" in subsystem Maltose and Maltodextrin Utilization or Trehalose Biosynthesis (EC 3.2.1.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LXQ7 at UniProt or InterPro

Protein Sequence (621 amino acids)

>MMP_RS06655 glycoside hydrolase family 15 protein (Methanococcus maripaludis S2)
MVGIIGNGNILAKIDDSGSIEYMFYPSLGYEKHIFDASFAIYNHGLRWAWDNDWEINQSY
VKDTNILRTTYECNEFLMESRDYIPISHNIIIKQISISNKTDETQDLKLFFYENLRMGEI
PRENTVQFIKDHKMIMKYDGMYSMCIGSDKKIDSYQCGVRSSDKSALIDISNGILKEYST
SSGLITDSAISWDLKLLPGQKQSVSVYIIMNEYKGDQYKLMETLASIKVVIDNHEDFYQL
TNSYWKNLLETTISKLSANELNRVSMCEDLCKRSLLTLLLLCDRGGGIMASPSLYPDYRH
VWCRDGGYIAVALSLCGQSSIVEKYFEWCKKTQNEDGSWVQSYYINGIPRLTAMQIDQVG
TTIWAALIHYRKSDNEKFLRKNWAMLKKAADYLSNAAIALSPSYDLWEEKYGVFTYTLGS
IYGGLKSAVEIAKILEENEGLVEKWQNSLKFLKEEVVEKIYLNDKNRFSKALHPNDDTVD
SSILGITVPFNLVNADDPRMVATADQIESAFTYKVGGIGRYPKDVYFGGNPWIINTLWLY
MYYELLIYSLSKNKAIKREILNNYREKSSNLFDWVCKYNFSGLMPEQIHKDLGVPISAMP
LGWSHAMFIIAVHGDFEILIP