Protein Info for MMP_RS06645 in Methanococcus maripaludis S2

Annotation: GTP-binding protein EngB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 230 PF01926: MMR_HSR1" amino acids 39 to 167 (129 residues), 62 bits, see alignment E=5.8e-21 PF02421: FeoB_N" amino acids 39 to 189 (151 residues), 45.8 bits, see alignment E=4.8e-16

Best Hits

Swiss-Prot: 100% identical to ENGB_METMP: Probable GTP-binding protein EngB (engB) from Methanococcus maripaludis (strain S2 / LL)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP1290)

Predicted SEED Role

"GTP-binding protein EngB" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LXQ9 at UniProt or InterPro

Protein Sequence (230 amino acids)

>MMP_RS06645 GTP-binding protein EngB (Methanococcus maripaludis S2)
MYENTNSEENNNNIQSQNMDIQKFKKYIRTEKKADERPKVIVMGRSNVGKSTFVKLVTGK
NVRVGKKPGVTLKITEYDMGTYILVDLPGFGFMEGIEKKAQEKIKDEIIHYVEDNKDAIA
ASIHILDAKSFIDIVERWGNKGEVPIDLEMADFLEELELNPIFVVNKMDKIKNSEWDNHL
DKVSETLGFLPPWRQWLDNFVPAIMRDNYGIDGIKHRINKRINIFKKSKK