Protein Info for MMP_RS06555 in Methanococcus maripaludis S2

Annotation: cupin domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 184 PF12844: HTH_19" amino acids 10 to 70 (61 residues), 47.9 bits, see alignment E=2.3e-16 PF01381: HTH_3" amino acids 12 to 64 (53 residues), 25.8 bits, see alignment E=1.8e-09 PF07883: Cupin_2" amino acids 112 to 182 (71 residues), 56 bits, see alignment E=5.2e-19 PF05899: Cupin_3" amino acids 130 to 173 (44 residues), 24.8 bits, see alignment E=2.8e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP1275)

Predicted SEED Role

"Transcriptional regulator, Hth-3 family" in subsystem Ketoisovalerate oxidoreductase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LXS3 at UniProt or InterPro

Protein Sequence (184 amino acids)

>MMP_RS06555 cupin domain-containing protein (Methanococcus maripaludis S2)
MTEKMKEIASRVRELRELSEISIEEMANHLQISPEIYQHYEEGTCDIPASVLYEIAHKFE
VDMGLLLTGEETRMHIFTVTRKGKGVSVERRKQYKYENLAEKFVHKKAEPFIVTVEPRTD
GKKPSKNSHPGQEFNYILEGSIKLYIHKNEVILEEGDSIFFDAGYEHAMEALNGKTAKFL
AIIM