Protein Info for MMP_RS06295 in Methanococcus maripaludis S2

Annotation: methanogenesis marker 14 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 492 PF09887: DUF2114" amino acids 43 to 485 (443 residues), 732.7 bits, see alignment E=6.7e-225 TIGR03285: putative methanogenesis marker protein 14" amino acids 44 to 487 (444 residues), 701.1 bits, see alignment E=2.7e-215

Best Hits

Swiss-Prot: 68% identical to Y1451_METJA: Uncharacterized protein MJ1451 (MJ1451) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP1223)

Predicted SEED Role

"Uncharacterized protein MJ1451"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LXX3 at UniProt or InterPro

Protein Sequence (492 amino acids)

>MMP_RS06295 methanogenesis marker 14 protein (Methanococcus maripaludis S2)
MGFLDSIKGIFSKSPKIHYAKSQSIDVMDLNPKRVGPNQHILPYYTVASVELGNTTTKAI
ISATEMGSGKTYVVSKEVRMTRDVRPPKKGEQVFGRTIWDVELTKEAVSEMVRDVLKGAM
DKAHLNVNDLHFVVRSTGVTAGFATPEEVGVMIVSLAEGCRMAGIPNGKMTPIMTKKQLP
EILQDYTLIEKLIFDGAVTGVVPPTGKEVVANEMEGELVTAGLKIGSKWTGVDYRNPCIS
IDFGTTLAGRITNNGEPYAKVVGNLCGLAGAVSDAVVRGTDLVNKRGGAVLDIHAEKGSP
NKELAKKYAEEIHEHVIIKEVPKGMERFGTVPVNPESAEKAGTFLIGCDVGENGSDIPEL
EKIGAKILKESNLPTLMYTLDIVSSKITQRLIKIAHEEGIINGDTAIGITGRAGITGEKP
KLIIELLSELGIWDNVSENIIFVEDGLALGASVMARCMNCLGTPKVPIGGKRNGPCILSQ
RIKRQKEMGMIK