Protein Info for MMP_RS06085 in Methanococcus maripaludis S2
Annotation: iron ABC transporter substrate-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02016, iron complex transport system substrate-binding protein (inferred from 100% identity to mmp:MMP1181)Predicted SEED Role
"Iron transport Periplasmic binding protein precursor"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (archaea)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q6LY12 at UniProt or InterPro
Protein Sequence (378 amino acids)
>MMP_RS06085 iron ABC transporter substrate-binding protein (Methanococcus maripaludis S2) MYKNGILAIILSLMIALSFSGCVDNTAQTSGETVKTVEIVDLAGRTVEVPEDVEKIVCSG PGALRLVTYLQADDMLVGVESCEQADITGAGKQYALAKPYTIANVDYFKTLPTIGTQFVD GLNCENIVNVNPDVIIISMSTAEVADNIQTKTGIPVVVLDYDEFESFTDKDLADPLTLLG KVLNREERAQAVINFFADAENDISNRISDVSDSEKPSVYVGGLNAAKGSHGIESTSSVFA PFEVLKAKNVAESIETKKQVYINKEQLIEWNPDIIFIDIAGYTSVINEDYEKNPEYYESL SAFKNGDVYLIYRYKSYMVDYGTVLANTYYIGTVLYPEEFSDIDPEAKADEIYEFLVGEA VYDKMAENFEGYTKLDLN