Protein Info for MMP_RS05835 in Methanococcus maripaludis S2

Annotation: secondary thiamine-phosphate synthase enzyme YjbQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 132 TIGR00149: secondary thiamine-phosphate synthase enzyme" amino acids 4 to 130 (127 residues), 165.2 bits, see alignment E=3.1e-53 PF01894: UPF0047" amino acids 17 to 129 (113 residues), 141.6 bits, see alignment E=6.4e-46

Best Hits

Swiss-Prot: 63% identical to Y1081_METJA: UPF0047 protein MJ1081 (MJ1081) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP1130)

Predicted SEED Role

"UPF0047 protein Bsu YugU"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LY61 at UniProt or InterPro

Protein Sequence (132 amino acids)

>MMP_RS05835 secondary thiamine-phosphate synthase enzyme YjbQ (Methanococcus maripaludis S2)
MFFEYSIKTDTRESLVDISDYILDAVTKSKVQNGVAIVFTPHTTSAITINENADPSVKKD
IVKFLHEKIPENYGFSHYEGNSDAHLKSSFFGPSLTLIINDGKIILGTWQGVYFCEFDGP
RSRKFYVKIMKD