Protein Info for MMP_RS05420 in Methanococcus maripaludis S2

Annotation: DUF61 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 129 PF01886: DUF61" amino acids 3 to 124 (122 residues), 123.4 bits, see alignment E=3.1e-40

Best Hits

Swiss-Prot: 59% identical to Y1224_METJA: UPF0216 protein MJ1224 (MJ1224) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K09737, hypothetical protein (inferred from 97% identity to mmx:MmarC6_1611)

Predicted SEED Role

"UPF0216 protein MTH_949"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LYE3 at UniProt or InterPro

Protein Sequence (129 amino acids)

>MMP_RS05420 DUF61 family protein (Methanococcus maripaludis S2)
MDKEIYKFLHNLKSNFKRKTLNELLKEDKPHLIVNGQRHRIKKKELEFIKENISKDIRLP
IVLEVDSSYDSGTVKIEGIEEVKLISKILGKKVSLFSEESILYIYKPELREVRRKLPTTT
QYLFRVGLN