Protein Info for MMP_RS05375 in Methanococcus maripaludis S2

Annotation: V-type ATP synthase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 686 transmembrane" amino acids 386 to 411 (26 residues), see Phobius details amino acids 423 to 446 (24 residues), see Phobius details amino acids 494 to 516 (23 residues), see Phobius details amino acids 528 to 580 (53 residues), see Phobius details amino acids 594 to 616 (23 residues), see Phobius details amino acids 622 to 645 (24 residues), see Phobius details PF01496: V_ATPase_I" amino acids 107 to 441 (335 residues), 59.5 bits, see alignment E=8.9e-21 amino acids 589 to 678 (90 residues), 45.4 bits, see alignment E=1.5e-16

Best Hits

Swiss-Prot: 58% identical to VATI_METJA: V-type ATP synthase subunit I (atpI) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K02123, V-type H+-transporting ATPase subunit I [EC: 3.6.3.14] (inferred from 100% identity to mmp:MMP1039)

Predicted SEED Role

"V-type ATP synthase subunit I (EC 3.6.3.14)" in subsystem V-Type ATP synthase (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LYF2 at UniProt or InterPro

Protein Sequence (686 amino acids)

>MMP_RS05375 V-type ATP synthase subunit I (Methanococcus maripaludis S2)
LRPARMNKIRAVILDEKVDPVIRQLHESGLVELYDLSAKLEDPEWNALMTPAPSAEYGRN
VASLTIKVSRLLDLFSSVSEGEKAGLSGVLNPKVPAKKKLSFSSSEEIISNVENVLESVE
GEVSEPAKKLAELENRKTILETLKDSVKYLSGFDLDLKFLGEGSYTYVVSGLVSQEDISE
LESSLEEATEGYVEIVKGNPVNKSEKEQKIPVIVATLKQCADVVGAELRKSGFERLDIAN
VEGTPSEIFNDTEKELLSIETETKAILENLNALSKKWTDEVLVLHEVLEIEKERAEAYSM
TGKTDRTHLIEAWTPKKHVKKVQEIIESASEGYAVVEVSEPDEPVEKIPVMLDNAKSVKP
FEMLTEMYAPPKYNEIDPTMMIMPGFLIFYGIMLTDAVYGLLLTLAGLVLWKRMGKVSSG
AYNLGYILTLSGLSTVFFGILTGGYLGDFMYQFLGMDIYTTGFALVNPLGESTYISAAKP
LLSLGGIDVNNGPMAILLFSIVAGIIHLFIGLTVGLKESLANGSVLDAFLNQGMWILLIL
AIVATVVTGNMMIAGGAVIAVIVLCMIKGFMNGGILDALLGAMDITGFLGNVLSYARLLA
LCLATGGLAMAVNIMAKLLGDAVPVIGILIAVVMLVFGHSFNFVMNGLGSFIHSLRLHYV
EFFGQYYEGGGKKFSPFKAKREYTSN